A pharmacogenomic profile of human neural progenitors undergoing differentiation in the presence of the traditional Chinese medicine NeuroAiD

NeuroAiD, a traditional Chinese medicine widely used to treat stroke patients in China, was recently demonstrated in rodent models and in clinical trials to possess neuroregenerative and neuroprotective properties. In order to understand the mechanisms employed by NeuroAiD to bring about its neuropr...

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Veröffentlicht in:	The pharmacogenomics journal 2016-10, Vol.16 (5), p.461-471
Hauptverfasser:	Chan, H Y A, Stanton, L W
Format:	Artikel
Sprache:	eng
Schlagworte:	13/100 14/63 38/61 38/90 692/617 82/51 Analysis Animal models Biomedical and Life Sciences Biomedicine Care and treatment Cell differentiation Cell Line Chinese medicine Clinical trials Drugs, Chinese Herbal - pharmacology Fibroblast growth factor 3 Gene Expression Gene Expression Profiling - methods Gene Expression Regulation - drug effects Gene Regulatory Networks - drug effects Genetic aspects Genome-Wide Association Study Health aspects Human Genetics Humans Neural stem cells Neural Stem Cells - drug effects Neural Stem Cells - metabolism Neurogenesis Neurogenesis - drug effects Neurogenesis - genetics Neuroglia - drug effects Neuroglia - metabolism Neurons - drug effects Neurons - metabolism Neuroprotection Neuroprotective Agents - pharmacology Oligonucleotide Array Sequence Analysis Oncology original-article Pharmacogenetics Pharmacogenomics Pharmacotherapy Psychopharmacology Stroke patients Stromelysin 2 Therapeutic targets Time Factors Traditional Chinese medicine
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