Naringenin inhibits spinal cord injury-induced activation of neutrophils through miR-223

Naringenin (NR), a flavonoid abundant in citrus fruits has been reported to possess anti-inflammatory properties. The present study aimed to investigate the protective of naringenin in rats after spinal cord injury (SCI) and the underlying mechanisms associated with neuroinflammation. Adult male Spr...

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Veröffentlicht in:	Gene 2016-10, Vol.592 (1), p.128-133
Hauptverfasser:	Shi, Long-Bao, Tang, Pei-Fu, Zhang, Wei, Zhao, Yan-Peng, Zhang, Li-Cheng, Zhang, Hao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Anti-Inflammatory Agents - therapeutic use Citrus Flavanones - pharmacology Flavanones - therapeutic use Interleukin-1beta - genetics Interleukin-1beta - metabolism Male MicroRNAs - genetics miR-223 Naringenin Neutrophil Activation Neutrophils Neutrophils - drug effects Neutrophils - immunology NLR Family, Pyrin Domain-Containing 3 Protein - genetics NLR Family, Pyrin Domain-Containing 3 Protein - metabolism Rats Rats, Sprague-Dawley Spinal Cord Injuries - drug therapy Spinal Cord Injuries - immunology Spinal cord injury
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