Association between STR -794 CATT5-8 and SNP-173 G/C polymorphisms in the MIF gene and lepromatous leprosy in Mestizo patients of western Mexico

Abstract Lepromatous leprosy (LL) is the most common presentation of leprosy in Mexico. LL patients are unable to activate an effective inflammatory response against Mycobacterium leprae probably due to the genetics of the host. Macrophage migration inhibitory factor (MIF) is important to trigger in...

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Veröffentlicht in:	Human immunology 2016-10, Vol.77 (10), p.985-989
Hauptverfasser:	Martinez-Guzman, M.A, Alvarado-Navarro, A, Pereira-Suarez, A.L, Muñoz-Valle, J.F, Fafutis-Morris, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Allergy and Immunology Female Gene Frequency Genetic Predisposition to Disease Genotype Humans Intramolecular Oxidoreductases - genetics Leprosy Leprosy, Lepromatous - genetics Macrophage Migration Inhibitory Factor Macrophage Migration-Inhibitory Factors - genetics Male Mexico Microsatellite Repeats - genetics Middle Aged Mycobacterium leprae Polymorphism, Single Nucleotide - genetics Polymorphisms Promoter Regions, Genetic - genetics
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