Glucagon-like peptide 1 receptor agonist (GLP-1 RA): long-term effect on kidney function in patients with type 2 diabetes

Abstract Aims In a short-term study including 31 patients with type 2 diabetes, glucagon-like peptide 1 receptor agonist (GLP-1 RA) treatment was associated with a significant reversible decline in GFR. Twenty-three patients re-initiated GLP-1 RA treatment after the primary study, and the aim was to...

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Veröffentlicht in:	Journal of diabetes and its complications 2015-07, Vol.29 (5), p.670-674
Hauptverfasser:	von Scholten, Bernt Johan, Hansen, Tine Willum, Goetze, Jens Peter, Persson, Frederik, Rossing, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Albuminuria - etiology Blood pressure Diabetes Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - drug therapy Diabetes Mellitus, Type 2 - metabolism Diabetes Mellitus, Type 2 - physiopathology Diabetic Nephropathies - physiopathology Diabetic Nephropathies - prevention & control Endocrinology & Metabolism Female Follow-Up Studies Glomerular filtration rate Glomerular Filtration Rate - drug effects GLP-1 Glucagon-Like Peptide-1 Receptor - agonists Glucagon-Like Peptide-1 Receptor - metabolism Glycated Hemoglobin A - analysis Heart rate Humans Hyperglycemia - prevention & control Hypoglycemic Agents - therapeutic use Kidney - drug effects Kidney - physiopathology Kidney function Kidneys Liraglutide Liraglutide - therapeutic use Male Middle Aged MR-proANP Renal Insufficiency - physiopathology Renal Insufficiency - prevention & control Rodents Statistical analysis Urinary albumin excretion rate Urine
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