Mono- and Combined Therapy of Metastasizing Breast Carcinoma 4T1 with Zoledronic Acid and Doxorubicin

The efficiency of monotherapy with zoledronic acid (Resorba), doxorubicin, and their combination was studied on the model of metastasizing breast carcinoma in BALB/c mice. Doxorubicin monotherapy was accompanied by a significant increase in median survival up to 57 days ( vs. 34 and 35 days in contr...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2016-08, Vol.161 (4), p.580-586
Hauptverfasser:	Baklaushev, V. P., Grinenko, N. F., Yusubalieva, G. M., Gubskii, I. L., Burenkov, M. S., Rabinovich, E. Z., Ivanova, N. V., Chekhonin, V. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anthracyclines Biomedical and Life Sciences Biomedicine Bone disorder agents Breast cancer Breast Neoplasms - drug therapy Breast Neoplasms - pathology Cancer metastasis Cancer treatment Carcinoma Cell Biology Development and progression Diphosphonates - therapeutic use Disease Models, Animal Doxorubicin - therapeutic use Female Imidazoles - therapeutic use Internal Medicine Laboratory Medicine Magnetic Resonance Imaging Mammary Neoplasms, Experimental - drug therapy Mammary Neoplasms, Experimental - pathology Mice Mice, Inbred BALB C Pathology Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
Online-Zugang:	Volltext
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