Development of an Advanced Primary Human In Vitro Model of the Small Intestine

Intestinal in vitro models are valuable tools in drug discovery and infection research. Despite several advantages, the standard cell line-based Transwell ® models based for example on colonic epithelial Caco-2 cells, lack the cellular complexity and transport activity associated with native small i...

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Veröffentlicht in:	Tissue engineering. Part C, Methods Methods, 2016-09, Vol.22 (9), p.873-883
Hauptverfasser:	Schweinlin, Matthias, Wilhelm, Sabine, Schwedhelm, Ivo, Hansmann, Jan, Rietscher, Rene, Jurowich, Christian, Walles, Heike, Metzger, Marco
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological Transport Cell Differentiation Coculture Techniques Digestive system Fibroblasts - cytology Humans In Vitro Techniques Infections Intestinal Mucosa - cytology Intestine, Small - cytology Medical research Models, Biological
Online-Zugang:	Volltext
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