Impact of HIV Infection on Mortality in a Cohort of Injection Drug Users
The prevalence of HIV has been rising among injection drug users (IDUs) and AIDS is now an important cause of death among that population. We tracked mortality and recorded detailed causes of death in the Vancouver Injection Drug Users Study (VIDUS). This is an open cohort of over 1,400 active IDUs...
Gespeichert in:
| Veröffentlicht in: | Journal of acquired immune deficiency syndromes (1999) 2001-12, Vol.28 (4), p.351-357 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 357 |
|---|---|
| container_issue | 4 |
| container_start_page | 351 |
| container_title | Journal of acquired immune deficiency syndromes (1999) |
| container_volume | 28 |
| creator | Tyndall, Mark W Craib, Kevin J. P Currie, Sue Li, Kathy OʼShaughnessy, Michael V Schechter, Martin T |
| description | The prevalence of HIV has been rising among injection drug users (IDUs) and AIDS is now an important cause of death among that population. We tracked mortality and recorded detailed causes of death in the Vancouver Injection Drug Users Study (VIDUS). This is an open cohort of over 1,400 active IDUs that began in May 1996. At enrollment and at semiannual follow-up visits, a trained interviewer administers a detailed semistructured questionnaire. Mortality was recorded during follow-up and detailed causes of death were collected from coronerʼs reports, hospital records, and the provincial (British Columbia) registry. Causes of death were obtained on 125 participants. Overall, the leading cause of death was overdose accounting for 25% of deaths among HIV-positive participants and 42% among HIV-negative participants. Of the 65 deaths among HIV-positive individuals, 22 (34%) were HIV related. Mortality was associated with older age (adjusted hazards ratio [AHR], 1.03 per year), HIV positivity (AHR, 2.67), injection cocaine use (AHR, 2.23) and methadone treatment (AHR, 0.47). The high rate of HIV in this population has added significantly to the burden of illness and death in this marginalized population. |
| doi_str_mv | 10.1097/00126334-200112010-00008 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_18272224</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>18272224</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4948-a0e9f8c33b0d1eb3dc806d5aac3fa1ae56a3027b5791c89254bd0997702f9de43</originalsourceid><addsrcrecordid>eNp1kd1q3DAQRkVoSLabvEIRhfbOzejHlnRZNk3XkJCbJLdCluWut15rK9mEvH3krNNAIGJgBnHmQxwhhAn8IKDEBQChBWM8o2kiFAhkkI48QguiOM-ElPxTmnOaZ5yw_BR9jnGb2IJzdYJOCREgCkEXaF3u9sYO2Dd4XT7gsm-cHVrf41Q3Pgyma4cn3PbY4JXfpIuJLPvtTF2G8Q--jy7EM3TcmC6687kv0f3Vr7vVOru-_V2ufl5nlisuMwNONdIyVkFNXMVqK6Goc2MsawwxLi8MAyqqXChipaI5r2pQSgigjaodZ0v0_ZC7D_7f6OKgd220rutM7_wYNZFUUEon8Os7cOvH0Ke3acpYwQVwkSB5gGzwMQbX6H1odyY8aQJ6Uq1fVev_qvWL6rT6Zc4fq52r3xZntwn4NgMmWtM1wfS2jW8cy6FQdAriB-7Rd0My-bcbH13QG2e6YaM_-mr2DPcXkzY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>233647047</pqid></control><display><type>article</type><title>Impact of HIV Infection on Mortality in a Cohort of Injection Drug Users</title><source>MEDLINE</source><source>Journals@Ovid LWW Legacy Archive</source><source>Journals@Ovid Complete</source><source>Free E- Journals</source><creator>Tyndall, Mark W ; Craib, Kevin J. P ; Currie, Sue ; Li, Kathy ; OʼShaughnessy, Michael V ; Schechter, Martin T</creator><creatorcontrib>Tyndall, Mark W ; Craib, Kevin J. P ; Currie, Sue ; Li, Kathy ; OʼShaughnessy, Michael V ; Schechter, Martin T</creatorcontrib><description>The prevalence of HIV has been rising among injection drug users (IDUs) and AIDS is now an important cause of death among that population. We tracked mortality and recorded detailed causes of death in the Vancouver Injection Drug Users Study (VIDUS). This is an open cohort of over 1,400 active IDUs that began in May 1996. At enrollment and at semiannual follow-up visits, a trained interviewer administers a detailed semistructured questionnaire. Mortality was recorded during follow-up and detailed causes of death were collected from coronerʼs reports, hospital records, and the provincial (British Columbia) registry. Causes of death were obtained on 125 participants. Overall, the leading cause of death was overdose accounting for 25% of deaths among HIV-positive participants and 42% among HIV-negative participants. Of the 65 deaths among HIV-positive individuals, 22 (34%) were HIV related. Mortality was associated with older age (adjusted hazards ratio [AHR], 1.03 per year), HIV positivity (AHR, 2.67), injection cocaine use (AHR, 2.23) and methadone treatment (AHR, 0.47). The high rate of HIV in this population has added significantly to the burden of illness and death in this marginalized population.</description><identifier>ISSN: 1525-4135</identifier><identifier>EISSN: 1944-7884</identifier><identifier>DOI: 10.1097/00126334-200112010-00008</identifier><identifier>PMID: 11707672</identifier><identifier>CODEN: JDSRET</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins, Inc</publisher><subject>Adolescent ; Adult ; Age Factors ; Aged ; Biological and medical sciences ; British Columbia - epidemiology ; Cause of Death ; Cocaine ; Cohort Studies ; Deaths ; Drug Overdose ; Drug use ; Experimental viral diseases and models ; Female ; HIV ; HIV Infections - epidemiology ; HIV Infections - mortality ; Human immunodeficiency virus ; Humans ; Infections ; Infectious diseases ; Injections ; Male ; Medical sciences ; Methadone - administration & dosage ; Middle Aged ; Miscellaneous ; Mortality ; Narcotics - administration & dosage ; Population Surveillance ; Public health. Hygiene ; Public health. Hygiene-occupational medicine ; Substance Abuse, Intravenous - epidemiology ; Substance Abuse, Intravenous - mortality ; Surveys and Questionnaires ; Viral diseases</subject><ispartof>Journal of acquired immune deficiency syndromes (1999), 2001-12, Vol.28 (4), p.351-357</ispartof><rights>2001 Lippincott Williams & Wilkins, Inc.</rights><rights>2002 INIST-CNRS</rights><rights>Copyright Lippincott Williams & Wilkins Dec 1, 2001</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4948-a0e9f8c33b0d1eb3dc806d5aac3fa1ae56a3027b5791c89254bd0997702f9de43</citedby><cites>FETCH-LOGICAL-c4948-a0e9f8c33b0d1eb3dc806d5aac3fa1ae56a3027b5791c89254bd0997702f9de43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf><![CDATA[$$Uhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&PDF=y&D=ovft&AN=00126334-200112010-00008$$EPDF$$P50$$Gwolterskluwer$$H]]></linktopdf><linktohtml>$$Uhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&NEWS=n&CSC=Y&PAGE=fulltext&D=ovft&AN=00126334-200112010-00008$$EHTML$$P50$$Gwolterskluwer$$H</linktohtml><link.rule.ids>314,780,784,4609,27924,27925,64666,65461</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=13506928$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11707672$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tyndall, Mark W</creatorcontrib><creatorcontrib>Craib, Kevin J. P</creatorcontrib><creatorcontrib>Currie, Sue</creatorcontrib><creatorcontrib>Li, Kathy</creatorcontrib><creatorcontrib>OʼShaughnessy, Michael V</creatorcontrib><creatorcontrib>Schechter, Martin T</creatorcontrib><title>Impact of HIV Infection on Mortality in a Cohort of Injection Drug Users</title><title>Journal of acquired immune deficiency syndromes (1999)</title><addtitle>J Acquir Immune Defic Syndr</addtitle><description>The prevalence of HIV has been rising among injection drug users (IDUs) and AIDS is now an important cause of death among that population. We tracked mortality and recorded detailed causes of death in the Vancouver Injection Drug Users Study (VIDUS). This is an open cohort of over 1,400 active IDUs that began in May 1996. At enrollment and at semiannual follow-up visits, a trained interviewer administers a detailed semistructured questionnaire. Mortality was recorded during follow-up and detailed causes of death were collected from coronerʼs reports, hospital records, and the provincial (British Columbia) registry. Causes of death were obtained on 125 participants. Overall, the leading cause of death was overdose accounting for 25% of deaths among HIV-positive participants and 42% among HIV-negative participants. Of the 65 deaths among HIV-positive individuals, 22 (34%) were HIV related. Mortality was associated with older age (adjusted hazards ratio [AHR], 1.03 per year), HIV positivity (AHR, 2.67), injection cocaine use (AHR, 2.23) and methadone treatment (AHR, 0.47). The high rate of HIV in this population has added significantly to the burden of illness and death in this marginalized population.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>British Columbia - epidemiology</subject><subject>Cause of Death</subject><subject>Cocaine</subject><subject>Cohort Studies</subject><subject>Deaths</subject><subject>Drug Overdose</subject><subject>Drug use</subject><subject>Experimental viral diseases and models</subject><subject>Female</subject><subject>HIV</subject><subject>HIV Infections - epidemiology</subject><subject>HIV Infections - mortality</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Injections</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Methadone - administration & dosage</subject><subject>Middle Aged</subject><subject>Miscellaneous</subject><subject>Mortality</subject><subject>Narcotics - administration & dosage</subject><subject>Population Surveillance</subject><subject>Public health. Hygiene</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Substance Abuse, Intravenous - epidemiology</subject><subject>Substance Abuse, Intravenous - mortality</subject><subject>Surveys and Questionnaires</subject><subject>Viral diseases</subject><issn>1525-4135</issn><issn>1944-7884</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kd1q3DAQRkVoSLabvEIRhfbOzejHlnRZNk3XkJCbJLdCluWut15rK9mEvH3krNNAIGJgBnHmQxwhhAn8IKDEBQChBWM8o2kiFAhkkI48QguiOM-ElPxTmnOaZ5yw_BR9jnGb2IJzdYJOCREgCkEXaF3u9sYO2Dd4XT7gsm-cHVrf41Q3Pgyma4cn3PbY4JXfpIuJLPvtTF2G8Q--jy7EM3TcmC6687kv0f3Vr7vVOru-_V2ufl5nlisuMwNONdIyVkFNXMVqK6Goc2MsawwxLi8MAyqqXChipaI5r2pQSgigjaodZ0v0_ZC7D_7f6OKgd220rutM7_wYNZFUUEon8Os7cOvH0Ke3acpYwQVwkSB5gGzwMQbX6H1odyY8aQJ6Uq1fVev_qvWL6rT6Zc4fq52r3xZntwn4NgMmWtM1wfS2jW8cy6FQdAriB-7Rd0My-bcbH13QG2e6YaM_-mr2DPcXkzY</recordid><startdate>20011201</startdate><enddate>20011201</enddate><creator>Tyndall, Mark W</creator><creator>Craib, Kevin J. P</creator><creator>Currie, Sue</creator><creator>Li, Kathy</creator><creator>OʼShaughnessy, Michael V</creator><creator>Schechter, Martin T</creator><general>Lippincott Williams & Wilkins, Inc</general><general>Lippincott Williams & Wilkins</general><general>Lippincott Williams & Wilkins Ovid Technologies</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T2</scope><scope>7T5</scope><scope>7TK</scope><scope>7U7</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope></search><sort><creationdate>20011201</creationdate><title>Impact of HIV Infection on Mortality in a Cohort of Injection Drug Users</title><author>Tyndall, Mark W ; Craib, Kevin J. P ; Currie, Sue ; Li, Kathy ; OʼShaughnessy, Michael V ; Schechter, Martin T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4948-a0e9f8c33b0d1eb3dc806d5aac3fa1ae56a3027b5791c89254bd0997702f9de43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>British Columbia - epidemiology</topic><topic>Cause of Death</topic><topic>Cocaine</topic><topic>Cohort Studies</topic><topic>Deaths</topic><topic>Drug Overdose</topic><topic>Drug use</topic><topic>Experimental viral diseases and models</topic><topic>Female</topic><topic>HIV</topic><topic>HIV Infections - epidemiology</topic><topic>HIV Infections - mortality</topic><topic>Human immunodeficiency virus</topic><topic>Humans</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>Injections</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Methadone - administration & dosage</topic><topic>Middle Aged</topic><topic>Miscellaneous</topic><topic>Mortality</topic><topic>Narcotics - administration & dosage</topic><topic>Population Surveillance</topic><topic>Public health. Hygiene</topic><topic>Public health. Hygiene-occupational medicine</topic><topic>Substance Abuse, Intravenous - epidemiology</topic><topic>Substance Abuse, Intravenous - mortality</topic><topic>Surveys and Questionnaires</topic><topic>Viral diseases</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tyndall, Mark W</creatorcontrib><creatorcontrib>Craib, Kevin J. P</creatorcontrib><creatorcontrib>Currie, Sue</creatorcontrib><creatorcontrib>Li, Kathy</creatorcontrib><creatorcontrib>OʼShaughnessy, Michael V</creatorcontrib><creatorcontrib>Schechter, Martin T</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Journal of acquired immune deficiency syndromes (1999)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tyndall, Mark W</au><au>Craib, Kevin J. P</au><au>Currie, Sue</au><au>Li, Kathy</au><au>OʼShaughnessy, Michael V</au><au>Schechter, Martin T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Impact of HIV Infection on Mortality in a Cohort of Injection Drug Users</atitle><jtitle>Journal of acquired immune deficiency syndromes (1999)</jtitle><addtitle>J Acquir Immune Defic Syndr</addtitle><date>2001-12-01</date><risdate>2001</risdate><volume>28</volume><issue>4</issue><spage>351</spage><epage>357</epage><pages>351-357</pages><issn>1525-4135</issn><eissn>1944-7884</eissn><coden>JDSRET</coden><abstract>The prevalence of HIV has been rising among injection drug users (IDUs) and AIDS is now an important cause of death among that population. We tracked mortality and recorded detailed causes of death in the Vancouver Injection Drug Users Study (VIDUS). This is an open cohort of over 1,400 active IDUs that began in May 1996. At enrollment and at semiannual follow-up visits, a trained interviewer administers a detailed semistructured questionnaire. Mortality was recorded during follow-up and detailed causes of death were collected from coronerʼs reports, hospital records, and the provincial (British Columbia) registry. Causes of death were obtained on 125 participants. Overall, the leading cause of death was overdose accounting for 25% of deaths among HIV-positive participants and 42% among HIV-negative participants. Of the 65 deaths among HIV-positive individuals, 22 (34%) were HIV related. Mortality was associated with older age (adjusted hazards ratio [AHR], 1.03 per year), HIV positivity (AHR, 2.67), injection cocaine use (AHR, 2.23) and methadone treatment (AHR, 0.47). The high rate of HIV in this population has added significantly to the burden of illness and death in this marginalized population.</abstract><cop>Hagerstown, MD</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>11707672</pmid><doi>10.1097/00126334-200112010-00008</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1525-4135 |
| ispartof | Journal of acquired immune deficiency syndromes (1999), 2001-12, Vol.28 (4), p.351-357 |
| issn | 1525-4135 1944-7884 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_18272224 |
| source | MEDLINE; Journals@Ovid LWW Legacy Archive; Journals@Ovid Complete; Free E- Journals |
| subjects | Adolescent Adult Age Factors Aged Biological and medical sciences British Columbia - epidemiology Cause of Death Cocaine Cohort Studies Deaths Drug Overdose Drug use Experimental viral diseases and models Female HIV HIV Infections - epidemiology HIV Infections - mortality Human immunodeficiency virus Humans Infections Infectious diseases Injections Male Medical sciences Methadone - administration & dosage Middle Aged Miscellaneous Mortality Narcotics - administration & dosage Population Surveillance Public health. Hygiene Public health. Hygiene-occupational medicine Substance Abuse, Intravenous - epidemiology Substance Abuse, Intravenous - mortality Surveys and Questionnaires Viral diseases |
| title | Impact of HIV Infection on Mortality in a Cohort of Injection Drug Users |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-22T08%3A02%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Impact%20of%20HIV%20Infection%20on%20Mortality%20in%20a%20Cohort%20of%20Injection%20Drug%20Users&rft.jtitle=Journal%20of%20acquired%20immune%20deficiency%20syndromes%20(1999)&rft.au=Tyndall,%20Mark%20W&rft.date=2001-12-01&rft.volume=28&rft.issue=4&rft.spage=351&rft.epage=357&rft.pages=351-357&rft.issn=1525-4135&rft.eissn=1944-7884&rft.coden=JDSRET&rft_id=info:doi/10.1097/00126334-200112010-00008&rft_dat=%3Cproquest_cross%3E18272224%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=233647047&rft_id=info:pmid/11707672&rfr_iscdi=true |