Drug metabolism polymorphisms as modulators of cancer susceptibility

Recently, several molecular genetic bases of polymorphic enzyme activities involved in drug activation and detoxification have been elucidated. Many molecular epidemiology studies based on these premises have sought to gather information on the association of genetically determined metabolic variant...

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Veröffentlicht in:	Mutation research 1999-05, Vol.436 (3), p.227-261
Hauptverfasser:	Taningher, Maurizio, Malacarne, Davide, Izzotti, Alberto, Ugolini, Donatella, Parodi, Silvio
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cancer risk Chemical carcinogenesis Classical genetics, quantitative genetics, hybrids Disease Susceptibility Drug metabolism Fundamental and applied biological sciences. Psychology Genetic polymorphism Genetics of eukaryotes. Biological and molecular evolution Human Humans Neoplasms - chemically induced Neoplasms - enzymology Neoplasms - genetics Pharmaceutical Preparations - metabolism Polymorphism, Genetic Risk Factors
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