Hypertensive Patients Exhibit an Altered Metabolism. a Specific Metabolite Signature in Urine is Able to Predict Albuminuria Progression

Abstract Hypertension is increasing in prevalence, and albuminuria is a strong indicator of cardiovascular risk and renal damage progression. Despite blood-pressure control with chronic treatment, a relevant sub-group of patients develop albuminuria. However, the biological factors responsible for a...

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Veröffentlicht in:	Translational research : the journal of laboratory and clinical medicine 2016-12, Vol.178, p.25-37.e7
Hauptverfasser:	Gonzalez-Calero, Laura, Martin-Lorenzo, Marta, Martínez, Paula J, Baldan-Martin, Montserrat, Ruiz-Hurtado, Gema, Segura, Julian, de la Cuesta, Fernando, Barderas, Maria G, Ruilope, Luis M, Vivanco, Fernando, Alvarez-Llamas, Gloria
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Albuminuria - metabolism Albuminuria - pathology Albuminuria - physiopathology Albuminuria - urine Disease Progression Female Glomerular Filtration Rate Humans Hypertension - complications Hypertension - metabolism Hypertension - physiopathology Hypertension - urine Internal Medicine Male Metabolic Networks and Pathways Metabolome Middle Aged Proton Magnetic Resonance Spectroscopy Renin-Angiotensin System
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