Deregulation of the protein phosphatase 2A, PP2A in cancer: complexity and therapeutic options

The complexity of the phosphatase, PP2A, is being unravelled and current research is increasingly providing information on the association of deregulated PP2A function with cancer initiation and progression. It has been reported that decreased activity of PP2A is a recurrent observation in many type...

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Veröffentlicht in:	Tumor biology 2016-09, Vol.37 (9), p.11691-11700
Hauptverfasser:	Grech, Godfrey, Baldacchino, Shawn, Saliba, Christian, Grixti, Maria Pia, Gauci, Robert, Petroni, Vanessa, Fenech, Anthony G., Scerri, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomedical and Life Sciences Biomedicine Breast cancer Cancer Research Cancer therapies Colorectal cancer Enzyme Activation Humans Kinases Neoplasms - drug therapy Neoplasms - enzymology Phosphates Protein Phosphatase 2 - antagonists & inhibitors Protein Phosphatase 2 - chemistry Protein Phosphatase 2 - physiology Protein Subunits Review
Online-Zugang:	Volltext
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