Structural biology of glutamate receptor ion channel complexes

•Resting active and desensitized state AMPA and kainate receptor structures.•First structure of an AMPA receptor TARP complex.•NMDA receptors adopt unexpected conformations. Chemical transmission at excitatory synapses in the brain is mediated by a diverse family of glutamate receptor ion channels (...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Current opinion in structural biology 2016-12, Vol.41, p.119-127
1. Verfasser:	Mayer, Mark L
Format:	Artikel
Sprache:	eng
Schlagworte:	Excitatory Amino Acid Antagonists - pharmacology Humans Ion Channel Gating Protein Conformation Receptors, Glutamate - chemistry Receptors, Glutamate - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!