Infraorbital nerve involvement on magnetic resonance imaging in European patients with IgG4-related ophthalmic disease: a specific sign
Objectives To measure the frequency of infraorbital nerve enlargement (IONE) on magnetic resonance imaging (MRI) in European patients suffering from an IgG4-related ophthalmic disease (IgG4-ROD) as compared to patients suffering from non-IgG4-related ophthalmic disease (non-IgG4-ROD). Methods From J...
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| Veröffentlicht in: | European radiology 2017-04, Vol.27 (4), p.1335-1343 |
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| creator | Soussan, J. Ben Deschamps, R. Sadik, J. C. Savatovsky, J. Deschamps, L. Puttermann, M. Zmuda, M. Heran, F. Galatoire, O. Picard, H. Lecler, A. |
| description | Objectives
To measure the frequency of infraorbital nerve enlargement (IONE) on magnetic resonance imaging (MRI) in European patients suffering from an IgG4-related ophthalmic disease (IgG4-ROD) as compared to patients suffering from non-IgG4-related ophthalmic disease (non-IgG4-ROD).
Methods
From January 2006 through April 2015, 132 patients were admitted for non-lymphoma, non-thyroid-related orbital inflammation. Thirty-eight had both pre-therapeutic orbital MRI and histopathological IgG4 immunostaining. Fifteen patients were classified as cases of IgG4-ROD and 23 patients as cases of non-IgG4-ROD. Two readers performed blinded analyses of MRI images. The main criterion was the presence of an IONE, defined as the infraorbital nerve diameter being greater than the optic nerve diameter in the coronal section.
Results
IONE was present in 53% (8/15) of IgG4-ROD cases whereas it was never present (0/23) in cases of non-IgG4-ROD (
P
< 0.0001). IONE was only present in cases where, on MRI, the inflammation of the inferior quadrant was present and in direct contact with the ION canal.
Conclusions
In European patients suffering from orbital inflammation, the presence of IONE on an MRI is a specific sign of IgG4-ROD. Recognition of this pattern may facilitate the accurate diagnosis for clinicians and allow for the adequate management and appropriate care of their patients.
Key points
•
IONE on an MRI is a specific sign of IgG4-ROD.
•
IONE recognition allows for a quicker diagnosis and appropriate management.
•
IONE appears when inflammation is in direct contact with the ION canal. |
| doi_str_mv | 10.1007/s00330-016-4481-5 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1826725513</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1826725513</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-9b54d01b16da822cb07fe879628e5b5e976106f39177e8be1891f1d6b75f8a3d3</originalsourceid><addsrcrecordid>eNp1kU2L1TAUhoMoznX0B7iRgBs31Zx8NIk7GcaZCwNudF3S9rQ3Q5vUpL3iL_Bvm8sdRQZcBU6e9004DyGvgb0HxvSHzJgQrGJQV1IaqNQTsgMpeAXMyKdkx6wwlbZWXpAXOd8zxixI_ZxccC1FzUDtyK99GJKLqfWrm2jAdETqwzFOR5wxrDQGOrsx4Oo7mjDH4EJXiDLzYSwkvd5SXNAFurjVl0SmP_x6oPvxRlYJJ7diT-NyWA9umktH7zO6jB-po3nBzg9llv0YXpJng5syvno4L8m3z9dfr26ruy83-6tPd1UnNF8r2yrZM2ih7p3hvGuZHtBoW3ODqlVodQ2sHoQFrdG0CMbCAH3dajUYJ3pxSd6de5cUv2-Y12b2ucNpcgHjlhswvNZcKRAFffsIvY9bCuV3hdJlf9JYVSg4U12KOSccmiWV9aSfDbDmZKk5W2qKpeZkqTll3jw0b-2M_d_EHy0F4Gcgl6swYvrn6f-2_gZbQp33</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1873604895</pqid></control><display><type>article</type><title>Infraorbital nerve involvement on magnetic resonance imaging in European patients with IgG4-related ophthalmic disease: a specific sign</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Soussan, J. Ben ; Deschamps, R. ; Sadik, J. C. ; Savatovsky, J. ; Deschamps, L. ; Puttermann, M. ; Zmuda, M. ; Heran, F. ; Galatoire, O. ; Picard, H. ; Lecler, A.</creator><creatorcontrib>Soussan, J. Ben ; Deschamps, R. ; Sadik, J. C. ; Savatovsky, J. ; Deschamps, L. ; Puttermann, M. ; Zmuda, M. ; Heran, F. ; Galatoire, O. ; Picard, H. ; Lecler, A.</creatorcontrib><description>Objectives
To measure the frequency of infraorbital nerve enlargement (IONE) on magnetic resonance imaging (MRI) in European patients suffering from an IgG4-related ophthalmic disease (IgG4-ROD) as compared to patients suffering from non-IgG4-related ophthalmic disease (non-IgG4-ROD).
Methods
From January 2006 through April 2015, 132 patients were admitted for non-lymphoma, non-thyroid-related orbital inflammation. Thirty-eight had both pre-therapeutic orbital MRI and histopathological IgG4 immunostaining. Fifteen patients were classified as cases of IgG4-ROD and 23 patients as cases of non-IgG4-ROD. Two readers performed blinded analyses of MRI images. The main criterion was the presence of an IONE, defined as the infraorbital nerve diameter being greater than the optic nerve diameter in the coronal section.
Results
IONE was present in 53% (8/15) of IgG4-ROD cases whereas it was never present (0/23) in cases of non-IgG4-ROD (
P
< 0.0001). IONE was only present in cases where, on MRI, the inflammation of the inferior quadrant was present and in direct contact with the ION canal.
Conclusions
In European patients suffering from orbital inflammation, the presence of IONE on an MRI is a specific sign of IgG4-ROD. Recognition of this pattern may facilitate the accurate diagnosis for clinicians and allow for the adequate management and appropriate care of their patients.
Key points
•
IONE on an MRI is a specific sign of IgG4-ROD.
•
IONE recognition allows for a quicker diagnosis and appropriate management.
•
IONE appears when inflammation is in direct contact with the ION canal.</description><identifier>ISSN: 0938-7994</identifier><identifier>EISSN: 1432-1084</identifier><identifier>DOI: 10.1007/s00330-016-4481-5</identifier><identifier>PMID: 27436015</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Diagnostic Radiology ; Disease ; Europe ; Exocrine glands ; Female ; Head and Neck ; Hospitals ; Humans ; Hypertrophy ; Imaging ; Immunoglobulin G - blood ; Inflammation ; Internal Medicine ; Interventional Radiology ; Lymphoma ; Magnetic resonance imaging ; Magnetic Resonance Imaging - methods ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Neuroradiology ; Optic Nerve - diagnostic imaging ; Optic Nerve - pathology ; Orbital Diseases - blood ; Orbital Diseases - diagnostic imaging ; Orbital Diseases - pathology ; Paraproteinemias - blood ; Paraproteinemias - diagnostic imaging ; Paraproteinemias - pathology ; Pathology ; Patients ; Radiology ; Retrospective Studies ; Thyroid gland ; Ultrasound</subject><ispartof>European radiology, 2017-04, Vol.27 (4), p.1335-1343</ispartof><rights>European Society of Radiology 2016</rights><rights>European Radiology is a copyright of Springer, 2017.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-9b54d01b16da822cb07fe879628e5b5e976106f39177e8be1891f1d6b75f8a3d3</citedby><cites>FETCH-LOGICAL-c372t-9b54d01b16da822cb07fe879628e5b5e976106f39177e8be1891f1d6b75f8a3d3</cites><orcidid>0000-0001-7869-1815</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00330-016-4481-5$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00330-016-4481-5$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27436015$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Soussan, J. Ben</creatorcontrib><creatorcontrib>Deschamps, R.</creatorcontrib><creatorcontrib>Sadik, J. C.</creatorcontrib><creatorcontrib>Savatovsky, J.</creatorcontrib><creatorcontrib>Deschamps, L.</creatorcontrib><creatorcontrib>Puttermann, M.</creatorcontrib><creatorcontrib>Zmuda, M.</creatorcontrib><creatorcontrib>Heran, F.</creatorcontrib><creatorcontrib>Galatoire, O.</creatorcontrib><creatorcontrib>Picard, H.</creatorcontrib><creatorcontrib>Lecler, A.</creatorcontrib><title>Infraorbital nerve involvement on magnetic resonance imaging in European patients with IgG4-related ophthalmic disease: a specific sign</title><title>European radiology</title><addtitle>Eur Radiol</addtitle><addtitle>Eur Radiol</addtitle><description>Objectives
To measure the frequency of infraorbital nerve enlargement (IONE) on magnetic resonance imaging (MRI) in European patients suffering from an IgG4-related ophthalmic disease (IgG4-ROD) as compared to patients suffering from non-IgG4-related ophthalmic disease (non-IgG4-ROD).
Methods
From January 2006 through April 2015, 132 patients were admitted for non-lymphoma, non-thyroid-related orbital inflammation. Thirty-eight had both pre-therapeutic orbital MRI and histopathological IgG4 immunostaining. Fifteen patients were classified as cases of IgG4-ROD and 23 patients as cases of non-IgG4-ROD. Two readers performed blinded analyses of MRI images. The main criterion was the presence of an IONE, defined as the infraorbital nerve diameter being greater than the optic nerve diameter in the coronal section.
Results
IONE was present in 53% (8/15) of IgG4-ROD cases whereas it was never present (0/23) in cases of non-IgG4-ROD (
P
< 0.0001). IONE was only present in cases where, on MRI, the inflammation of the inferior quadrant was present and in direct contact with the ION canal.
Conclusions
In European patients suffering from orbital inflammation, the presence of IONE on an MRI is a specific sign of IgG4-ROD. Recognition of this pattern may facilitate the accurate diagnosis for clinicians and allow for the adequate management and appropriate care of their patients.
Key points
•
IONE on an MRI is a specific sign of IgG4-ROD.
•
IONE recognition allows for a quicker diagnosis and appropriate management.
•
IONE appears when inflammation is in direct contact with the ION canal.</description><subject>Diagnostic Radiology</subject><subject>Disease</subject><subject>Europe</subject><subject>Exocrine glands</subject><subject>Female</subject><subject>Head and Neck</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Hypertrophy</subject><subject>Imaging</subject><subject>Immunoglobulin G - blood</subject><subject>Inflammation</subject><subject>Internal Medicine</subject><subject>Interventional Radiology</subject><subject>Lymphoma</subject><subject>Magnetic resonance imaging</subject><subject>Magnetic Resonance Imaging - methods</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Neuroradiology</subject><subject>Optic Nerve - diagnostic imaging</subject><subject>Optic Nerve - pathology</subject><subject>Orbital Diseases - blood</subject><subject>Orbital Diseases - diagnostic imaging</subject><subject>Orbital Diseases - pathology</subject><subject>Paraproteinemias - blood</subject><subject>Paraproteinemias - diagnostic imaging</subject><subject>Paraproteinemias - pathology</subject><subject>Pathology</subject><subject>Patients</subject><subject>Radiology</subject><subject>Retrospective Studies</subject><subject>Thyroid gland</subject><subject>Ultrasound</subject><issn>0938-7994</issn><issn>1432-1084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kU2L1TAUhoMoznX0B7iRgBs31Zx8NIk7GcaZCwNudF3S9rQ3Q5vUpL3iL_Bvm8sdRQZcBU6e9004DyGvgb0HxvSHzJgQrGJQV1IaqNQTsgMpeAXMyKdkx6wwlbZWXpAXOd8zxixI_ZxccC1FzUDtyK99GJKLqfWrm2jAdETqwzFOR5wxrDQGOrsx4Oo7mjDH4EJXiDLzYSwkvd5SXNAFurjVl0SmP_x6oPvxRlYJJ7diT-NyWA9umktH7zO6jB-po3nBzg9llv0YXpJng5syvno4L8m3z9dfr26ruy83-6tPd1UnNF8r2yrZM2ih7p3hvGuZHtBoW3ODqlVodQ2sHoQFrdG0CMbCAH3dajUYJ3pxSd6de5cUv2-Y12b2ucNpcgHjlhswvNZcKRAFffsIvY9bCuV3hdJlf9JYVSg4U12KOSccmiWV9aSfDbDmZKk5W2qKpeZkqTll3jw0b-2M_d_EHy0F4Gcgl6swYvrn6f-2_gZbQp33</recordid><startdate>20170401</startdate><enddate>20170401</enddate><creator>Soussan, J. Ben</creator><creator>Deschamps, R.</creator><creator>Sadik, J. C.</creator><creator>Savatovsky, J.</creator><creator>Deschamps, L.</creator><creator>Puttermann, M.</creator><creator>Zmuda, M.</creator><creator>Heran, F.</creator><creator>Galatoire, O.</creator><creator>Picard, H.</creator><creator>Lecler, A.</creator><general>Springer Berlin Heidelberg</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P5Z</scope><scope>P62</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-7869-1815</orcidid></search><sort><creationdate>20170401</creationdate><title>Infraorbital nerve involvement on magnetic resonance imaging in European patients with IgG4-related ophthalmic disease: a specific sign</title><author>Soussan, J. Ben ; Deschamps, R. ; Sadik, J. C. ; Savatovsky, J. ; Deschamps, L. ; Puttermann, M. ; Zmuda, M. ; Heran, F. ; Galatoire, O. ; Picard, H. ; Lecler, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-9b54d01b16da822cb07fe879628e5b5e976106f39177e8be1891f1d6b75f8a3d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Diagnostic Radiology</topic><topic>Disease</topic><topic>Europe</topic><topic>Exocrine glands</topic><topic>Female</topic><topic>Head and Neck</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Hypertrophy</topic><topic>Imaging</topic><topic>Immunoglobulin G - blood</topic><topic>Inflammation</topic><topic>Internal Medicine</topic><topic>Interventional Radiology</topic><topic>Lymphoma</topic><topic>Magnetic resonance imaging</topic><topic>Magnetic Resonance Imaging - methods</topic><topic>Male</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Middle Aged</topic><topic>Neuroradiology</topic><topic>Optic Nerve - diagnostic imaging</topic><topic>Optic Nerve - pathology</topic><topic>Orbital Diseases - blood</topic><topic>Orbital Diseases - diagnostic imaging</topic><topic>Orbital Diseases - pathology</topic><topic>Paraproteinemias - blood</topic><topic>Paraproteinemias - diagnostic imaging</topic><topic>Paraproteinemias - pathology</topic><topic>Pathology</topic><topic>Patients</topic><topic>Radiology</topic><topic>Retrospective Studies</topic><topic>Thyroid gland</topic><topic>Ultrasound</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Soussan, J. Ben</creatorcontrib><creatorcontrib>Deschamps, R.</creatorcontrib><creatorcontrib>Sadik, J. C.</creatorcontrib><creatorcontrib>Savatovsky, J.</creatorcontrib><creatorcontrib>Deschamps, L.</creatorcontrib><creatorcontrib>Puttermann, M.</creatorcontrib><creatorcontrib>Zmuda, M.</creatorcontrib><creatorcontrib>Heran, F.</creatorcontrib><creatorcontrib>Galatoire, O.</creatorcontrib><creatorcontrib>Picard, H.</creatorcontrib><creatorcontrib>Lecler, A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Advanced Technologies & Aerospace Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Advanced Technologies & Aerospace Database</collection><collection>ProQuest Advanced Technologies & Aerospace Collection</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>European radiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Soussan, J. Ben</au><au>Deschamps, R.</au><au>Sadik, J. C.</au><au>Savatovsky, J.</au><au>Deschamps, L.</au><au>Puttermann, M.</au><au>Zmuda, M.</au><au>Heran, F.</au><au>Galatoire, O.</au><au>Picard, H.</au><au>Lecler, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Infraorbital nerve involvement on magnetic resonance imaging in European patients with IgG4-related ophthalmic disease: a specific sign</atitle><jtitle>European radiology</jtitle><stitle>Eur Radiol</stitle><addtitle>Eur Radiol</addtitle><date>2017-04-01</date><risdate>2017</risdate><volume>27</volume><issue>4</issue><spage>1335</spage><epage>1343</epage><pages>1335-1343</pages><issn>0938-7994</issn><eissn>1432-1084</eissn><abstract>Objectives
To measure the frequency of infraorbital nerve enlargement (IONE) on magnetic resonance imaging (MRI) in European patients suffering from an IgG4-related ophthalmic disease (IgG4-ROD) as compared to patients suffering from non-IgG4-related ophthalmic disease (non-IgG4-ROD).
Methods
From January 2006 through April 2015, 132 patients were admitted for non-lymphoma, non-thyroid-related orbital inflammation. Thirty-eight had both pre-therapeutic orbital MRI and histopathological IgG4 immunostaining. Fifteen patients were classified as cases of IgG4-ROD and 23 patients as cases of non-IgG4-ROD. Two readers performed blinded analyses of MRI images. The main criterion was the presence of an IONE, defined as the infraorbital nerve diameter being greater than the optic nerve diameter in the coronal section.
Results
IONE was present in 53% (8/15) of IgG4-ROD cases whereas it was never present (0/23) in cases of non-IgG4-ROD (
P
< 0.0001). IONE was only present in cases where, on MRI, the inflammation of the inferior quadrant was present and in direct contact with the ION canal.
Conclusions
In European patients suffering from orbital inflammation, the presence of IONE on an MRI is a specific sign of IgG4-ROD. Recognition of this pattern may facilitate the accurate diagnosis for clinicians and allow for the adequate management and appropriate care of their patients.
Key points
•
IONE on an MRI is a specific sign of IgG4-ROD.
•
IONE recognition allows for a quicker diagnosis and appropriate management.
•
IONE appears when inflammation is in direct contact with the ION canal.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>27436015</pmid><doi>10.1007/s00330-016-4481-5</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0001-7869-1815</orcidid></addata></record> |
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| ispartof | European radiology, 2017-04, Vol.27 (4), p.1335-1343 |
| issn | 0938-7994 1432-1084 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Diagnostic Radiology Disease Europe Exocrine glands Female Head and Neck Hospitals Humans Hypertrophy Imaging Immunoglobulin G - blood Inflammation Internal Medicine Interventional Radiology Lymphoma Magnetic resonance imaging Magnetic Resonance Imaging - methods Male Medicine Medicine & Public Health Middle Aged Neuroradiology Optic Nerve - diagnostic imaging Optic Nerve - pathology Orbital Diseases - blood Orbital Diseases - diagnostic imaging Orbital Diseases - pathology Paraproteinemias - blood Paraproteinemias - diagnostic imaging Paraproteinemias - pathology Pathology Patients Radiology Retrospective Studies Thyroid gland Ultrasound |
| title | Infraorbital nerve involvement on magnetic resonance imaging in European patients with IgG4-related ophthalmic disease: a specific sign |
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