One-Pot Coupling–Coupling–Cyclocondensation Synthesis of Fluorescent Pyrazoles

Consecutive four-component coupling–coupling–cyclocondensation syntheses of pyrazoles and pyrimidines were developed by taking advantage of the provisional, sequentially Pd-catalyzed one-pot generation of alkynones from aryl iodides, ethynylmagnesium bromide, and acid chlorides. This one-pot methodo...

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Veröffentlicht in:	Journal of organic chemistry 2016-11, Vol.81 (21), p.10328-10338
Hauptverfasser:	Götzinger, Alissa C, Theßeling, Florian A, Hoppe, Corinna, Müller, Thomas J. J
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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