Portal Venous Blood Circulation Supports Immunosuppressive Environment and Pancreatic Cancer Circulating Tumor Cell Activation

Aggressive spread and liver metastases are predominant features of pancreatic ductal adenocarcinoma (PDAC). This study investigates activation of PDAC circulating tumor cells (CTC) and immunosuppression in the portal venous system. Portal venous and peripheral blood were collected during pancreatico...

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Veröffentlicht in:	Pancreas 2017-01, Vol.46 (1), p.116-123
Hauptverfasser:	Arnoletti, Juan Pablo, Zhu, Xiang, Almodovar, Alvin J O, Veldhuis, Paula P, Sause, Ryan, Griffith, Elizabeth, Corpus, George, Chang, Jeffrey C C, Fanaian, Naʼim, Litherland, Sally A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Blood Circulation Carcinoma, Pancreatic Ductal - blood Carcinoma, Pancreatic Ductal - genetics Carcinoma, Pancreatic Ductal - pathology Female Gene Expression Regulation, Neoplastic Humans Male Middle Aged Mutation Neoplastic Cells, Circulating - metabolism Pancreatic Neoplasms - blood Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology Portal Vein Proto-Oncogene Proteins p21(ras) - genetics
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