Filtration markers and determination methods for the assessment of kidney function
Estimation of renal function is crucial for a number of clinical situations. Endogenous markers such as creatinine, as well as several exogenous agents including inulin, 99mTc-DTPA and iothalamate are used for evaluation of kidney function. At present, new generation filtration markers and determina...
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Veröffentlicht in: | European journal of pharmacology 2016-11, Vol.790, p.92-98 |
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container_title | European journal of pharmacology |
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creator | Huang, Jiaguo Gretz, Norbert Weinfurter, Stefanie |
description | Estimation of renal function is crucial for a number of clinical situations. Endogenous markers such as creatinine, as well as several exogenous agents including inulin, 99mTc-DTPA and iothalamate are used for evaluation of kidney function. At present, new generation filtration markers and determination methods based on organic fluorescent dyes and fluorescent detection technique are developed. This review gives an overview of filtration markers and clearance methods for the assessment of kidney function. New filtration markers and transcutaneous measurement of renal function are described. Problems and issues relating to the reabsorption or secretion of each of markers and the applicability of methods are also discussed. |
doi_str_mv | 10.1016/j.ejphar.2016.06.060 |
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Endogenous markers such as creatinine, as well as several exogenous agents including inulin, 99mTc-DTPA and iothalamate are used for evaluation of kidney function. At present, new generation filtration markers and determination methods based on organic fluorescent dyes and fluorescent detection technique are developed. This review gives an overview of filtration markers and clearance methods for the assessment of kidney function. New filtration markers and transcutaneous measurement of renal function are described. Problems and issues relating to the reabsorption or secretion of each of markers and the applicability of methods are also discussed.</description><identifier>ISSN: 0014-2999</identifier><identifier>EISSN: 1879-0712</identifier><identifier>DOI: 10.1016/j.ejphar.2016.06.060</identifier><identifier>PMID: 27377216</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Animals ; Biomarkers - metabolism ; Clearance methods ; Filtration markers ; Fluorescent Dyes - metabolism ; Fluorescent markers ; Glomerular Filtration Rate ; Humans ; Kidney function ; Kidney Function Tests - methods ; Transcutaneous measurement</subject><ispartof>European journal of pharmacology, 2016-11, Vol.790, p.92-98</ispartof><rights>2016 Elsevier B.V.</rights><rights>Copyright © 2016 Elsevier B.V. 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Endogenous markers such as creatinine, as well as several exogenous agents including inulin, 99mTc-DTPA and iothalamate are used for evaluation of kidney function. At present, new generation filtration markers and determination methods based on organic fluorescent dyes and fluorescent detection technique are developed. This review gives an overview of filtration markers and clearance methods for the assessment of kidney function. New filtration markers and transcutaneous measurement of renal function are described. Problems and issues relating to the reabsorption or secretion of each of markers and the applicability of methods are also discussed.</description><subject>Animals</subject><subject>Biomarkers - metabolism</subject><subject>Clearance methods</subject><subject>Filtration markers</subject><subject>Fluorescent Dyes - metabolism</subject><subject>Fluorescent markers</subject><subject>Glomerular Filtration Rate</subject><subject>Humans</subject><subject>Kidney function</subject><subject>Kidney Function Tests - methods</subject><subject>Transcutaneous measurement</subject><issn>0014-2999</issn><issn>1879-0712</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kN9LwzAQgIMobk7_A5E8-tKZH13avAgiToWBIPocsuTC0q3tTFJh_70tnT4KB0e473J3H0LXlMwpoeKumkO13-gwZ_1rToYgJ2hKy0JmpKDsFE0JoXnGpJQTdBFjRQhZSLY4RxNW8KJgVEzR-9LvUtDJtw2uddhCiFg3FltIEGrfHCuQNq2N2LUBpw1gHSPEWEOTcOvw1tsGDth1jRnoS3Tm9C7C1THP0Ofy6ePxJVu9Pb8-PqwywwVLmZAaZL7m2nCz5gVzRjMnLRWUFbngOTOl5qUUmmsnnOTWmTw30G--KIFIwWfodvx3H9qvDmJStY8GdjvdQNtFRUsmeg9Ukh7NR9SENsYATu2D7889KErUYFNVarSpBpuKDDG03RwndOsa7F_Tr74euB8B6O_89hBUNB4aA9YHMEnZ1v8_4QeXZIjB</recordid><startdate>20161105</startdate><enddate>20161105</enddate><creator>Huang, Jiaguo</creator><creator>Gretz, Norbert</creator><creator>Weinfurter, Stefanie</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20161105</creationdate><title>Filtration markers and determination methods for the assessment of kidney function</title><author>Huang, Jiaguo ; Gretz, Norbert ; Weinfurter, Stefanie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c362t-69ae94b3ac3cb372fca2f9d1612746342c8a3896a3af6f93dfc44ce73758e0963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Animals</topic><topic>Biomarkers - metabolism</topic><topic>Clearance methods</topic><topic>Filtration markers</topic><topic>Fluorescent Dyes - metabolism</topic><topic>Fluorescent markers</topic><topic>Glomerular Filtration Rate</topic><topic>Humans</topic><topic>Kidney function</topic><topic>Kidney Function Tests - methods</topic><topic>Transcutaneous measurement</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Huang, Jiaguo</creatorcontrib><creatorcontrib>Gretz, Norbert</creatorcontrib><creatorcontrib>Weinfurter, Stefanie</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>European journal of pharmacology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Huang, Jiaguo</au><au>Gretz, Norbert</au><au>Weinfurter, Stefanie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Filtration markers and determination methods for the assessment of kidney function</atitle><jtitle>European journal of pharmacology</jtitle><addtitle>Eur J Pharmacol</addtitle><date>2016-11-05</date><risdate>2016</risdate><volume>790</volume><spage>92</spage><epage>98</epage><pages>92-98</pages><issn>0014-2999</issn><eissn>1879-0712</eissn><abstract>Estimation of renal function is crucial for a number of clinical situations. 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subjects | Animals Biomarkers - metabolism Clearance methods Filtration markers Fluorescent Dyes - metabolism Fluorescent markers Glomerular Filtration Rate Humans Kidney function Kidney Function Tests - methods Transcutaneous measurement |
title | Filtration markers and determination methods for the assessment of kidney function |
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