Prospective observational study to compare oral topical metronidazole versus 0.2% chlorhexidine gluconate to prevent nosocomial pneumonia
Highlights • We investigated the long-term effectiveness of oral hygiene with chlorhexidine gluconate in prevention of nosocomial pneumonia in a medical-surgical intensive care unit. • Chlorhexidine gluconate (0.2%) may reduce the incidence of nosocomial pneumonia and ventilator-associated pneumonia...
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| Veröffentlicht in: | American journal of infection control 2016-10, Vol.44 (10), p.1116-1122 |
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| creator | Chen, Ying, MD, PhD Mao, En-Qiang, MD, PhD Yang, Yi-Jun, RN Zhao, Shu-Yuan, RN Zhu, Cheng, MD Wang, Xiao-Fei, MD, PhD Jing, Feng, RN Sheng, Hui-Qiu, MD Yang, Zhi-Tao, MD, PhD Chen, Er-Zhen, MD, PhD |
| description | Highlights • We investigated the long-term effectiveness of oral hygiene with chlorhexidine gluconate in prevention of nosocomial pneumonia in a medical-surgical intensive care unit. • Chlorhexidine gluconate (0.2%) may reduce the incidence of nosocomial pneumonia and ventilator-associated pneumonia in an intensive care unit, but not in microbiologic epidemiology when noted. • Oral hygiene with 0.2% chlorhexidine gluconate showed a benefit in the prevention of nosocomial pneumonia, including ventilator-associated pneumonia in intensive care units, considering the safety and less selective pressure of antibiotic resistance. |
| doi_str_mv | 10.1016/j.ajic.2016.03.054 |
| format | Article |
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| subjects | Acinetobacter baumannii - isolation & purification Adult Aged Aged, 80 and over Bacteriology Chlorhexidine - analogs & derivatives Chlorhexidine - therapeutic use Chlorhexidine gluconate Cross Infection - prevention & control Effectiveness studies Female Humans Infection Control Infectious Disease Intensive care Intensive Care Units Intubation Male Metronidazole - therapeutic use Middle Aged Nosocomial infections Nosocomial pneumonia Oral Hygiene Pneumonia Pneumonia, Ventilator-Associated - microbiology Pneumonia, Ventilator-Associated - prevention & control Prospective Studies Ventilator-associated pneumonia |
| title | Prospective observational study to compare oral topical metronidazole versus 0.2% chlorhexidine gluconate to prevent nosocomial pneumonia |
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