Alteration in molecular markers of oocyte development and intersex condition in mullets impacted by wastewater treatment plant effluents
Highlights • Intersex mullets were described in two populations inhabiting downstream WWTPs. • Up-regulation of vtga was detected in both mullet populations. • Transcription of sex related genes showed impaired gametogenesis in mullets from Gernika. • Xenoestrogenicity and exposure to EDCs was demon...
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| Veröffentlicht in: | General and comparative endocrinology 2017-05, Vol.245, p.10-18 |
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| container_title | General and comparative endocrinology |
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| creator | Valencia, Ainara Rojo-Bartolomé, Iratxe Bizarro, Cristina Cancio, Ibon Ortiz-Zarragoitia, Maren |
| description | Highlights • Intersex mullets were described in two populations inhabiting downstream WWTPs. • Up-regulation of vtga was detected in both mullet populations. • Transcription of sex related genes showed impaired gametogenesis in mullets from Gernika. • Xenoestrogenicity and exposure to EDCs was demonstrated in both mullet populations. |
| doi_str_mv | 10.1016/j.ygcen.2016.06.017 |
| format | Article |
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Rojo-Bartolomé, Iratxe ; Bizarro, Cristina ; Cancio, Ibon ; Ortiz-Zarragoitia, Maren</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c459t-ef683e5ac574813a433e0c70b0de3b7164fb7b31eb9428c76d1589ae61e2e5e93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Animals</topic><topic>Chelon labrosus</topic><topic>Disorders of Sex Development - chemically induced</topic><topic>Disorders of Sex Development - veterinary</topic><topic>Endocrine Disruptors - chemistry</topic><topic>Endocrine Disruptors - toxicity</topic><topic>Endocrinology & Metabolism</topic><topic>Gametogenesis</topic><topic>Gametogenesis molecular markers</topic><topic>Gonads - drug effects</topic><topic>Intersex condition</topic><topic>Male</topic><topic>Oocytes - drug effects</topic><topic>Smegmamorpha - abnormalities</topic><topic>Up-Regulation</topic><topic>Vitellogenins - genetics</topic><topic>Waste Water</topic><topic>Wastewater treatment plant effluents</topic><topic>Water Pollutants, Chemical - toxicity</topic><topic>Xenoestrogenicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Valencia, Ainara</creatorcontrib><creatorcontrib>Rojo-Bartolomé, Iratxe</creatorcontrib><creatorcontrib>Bizarro, Cristina</creatorcontrib><creatorcontrib>Cancio, Ibon</creatorcontrib><creatorcontrib>Ortiz-Zarragoitia, Maren</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>General and comparative endocrinology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Valencia, Ainara</au><au>Rojo-Bartolomé, Iratxe</au><au>Bizarro, Cristina</au><au>Cancio, Ibon</au><au>Ortiz-Zarragoitia, Maren</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Alteration in molecular markers of oocyte development and intersex condition in mullets impacted by wastewater treatment plant effluents</atitle><jtitle>General and comparative endocrinology</jtitle><addtitle>Gen Comp Endocrinol</addtitle><date>2017-05-01</date><risdate>2017</risdate><volume>245</volume><spage>10</spage><epage>18</epage><pages>10-18</pages><issn>0016-6480</issn><eissn>1095-6840</eissn><abstract>Highlights • Intersex mullets were described in two populations inhabiting downstream WWTPs. • Up-regulation of vtga was detected in both mullet populations. • Transcription of sex related genes showed impaired gametogenesis in mullets from Gernika. • Xenoestrogenicity and exposure to EDCs was demonstrated in both mullet populations.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>27296671</pmid><doi>10.1016/j.ygcen.2016.06.017</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-2664-1303</orcidid><oa>free_for_read</oa></addata></record> |
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| ispartof | General and comparative endocrinology, 2017-05, Vol.245, p.10-18 |
| issn | 0016-6480 1095-6840 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Chelon labrosus Disorders of Sex Development - chemically induced Disorders of Sex Development - veterinary Endocrine Disruptors - chemistry Endocrine Disruptors - toxicity Endocrinology & Metabolism Gametogenesis Gametogenesis molecular markers Gonads - drug effects Intersex condition Male Oocytes - drug effects Smegmamorpha - abnormalities Up-Regulation Vitellogenins - genetics Waste Water Wastewater treatment plant effluents Water Pollutants, Chemical - toxicity Xenoestrogenicity |
| title | Alteration in molecular markers of oocyte development and intersex condition in mullets impacted by wastewater treatment plant effluents |
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