Tomographic Pharyngeal Dimensions in Individuals with Unilateral Cleft Lip/Palate and Class III Malocclusion are Reduced When Compared with Controls

Objective The objective of this study was to three-dimensionally evaluate the pharyngeal dimensions of individuals with complete nonsyndromic unilateral cleft lip and palate (UCLP) using cone beam computed tomography. Design This was a cross-sectional prospective study. Setting The study took place...

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Veröffentlicht in:The Cleft palate-craniofacial journal 2017-09, Vol.54 (5), p.502-508
Hauptverfasser: Ivy Kiemle, Trindade-Suedam, Thiago, Freire Lima, Letícia, Dominguez Campos, Renato Yassutaka, Faria Yaedú, Hugo Nary, Filho, Inge Elly, Kiemle Trindade
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container_end_page 508
container_issue 5
container_start_page 502
container_title The Cleft palate-craniofacial journal
container_volume 54
creator Ivy Kiemle, Trindade-Suedam
Thiago, Freire Lima
Letícia, Dominguez Campos
Renato Yassutaka, Faria Yaedú
Hugo Nary, Filho
Inge Elly, Kiemle Trindade
description Objective The objective of this study was to three-dimensionally evaluate the pharyngeal dimensions of individuals with complete nonsyndromic unilateral cleft lip and palate (UCLP) using cone beam computed tomography. Design This was a cross-sectional prospective study. Setting The study took place at the Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru-SP, Brazil. Patients and Participants The control group (CON) consisted of 23 noncleft adults with class III malocclusion, and the cleft group (UCLP) consisted of 22 individuals with UCLP and class III malocclusion. Two subgroups of individuals with class III malocclusion as a result of maxillary retrusion with (UCLP'; n = 19) and without (CON'; n = 8) clefts were also assessed. Interventions Pharyngeal volume, pharyngeal minimal cross-sectional area (CSA), location of CSA, pharyngeal length, sella-nasion-A point angle (SNA), sella-nasion-B point angle (SNB), and A point-nasion-B point angle (ANB), and body mass index were assessed using Dolphin software. Main Outcome Measure The pharyngeal dimensions of UCLP individuals are smaller when compared with controls. Results Mean pharyngeal volume (standard deviation) for the UCLP patients (20.8 [3.9] cm3) and the UCLP’ patients (20.3 [3.9] cm3) were significantly decreased when compared with the CON (28.2 [10.0] cm3) and CON’ patients (29.1 [10.2] cm3), respectively. No differences were found in the pharyngeal minimal CSA, ANB, or pharyngeal length values between groups (CON versus UCLP and CON’ versus UCLP'). CSAs were located mostly at the oropharynx, except in the UCLP’ patients, which were mainly at the hypopharynx. Mean SNA in the UCLP (76.4° [4.6°]) and UCLP’ groups (75.1 [3.1°]) were significantly smaller than those in the CON (82.8° [4.1°]) and CON’ groups (78.6° [1.2°]). SNB values were statistically smaller only for the comparison of CON versus UCLP patients. Conclusion The pharynx of individuals with UCLP and class III malocclusion is volumetrically smaller than that of individuals with class III malocclusion and no clefts.
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Design This was a cross-sectional prospective study. Setting The study took place at the Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru-SP, Brazil. Patients and Participants The control group (CON) consisted of 23 noncleft adults with class III malocclusion, and the cleft group (UCLP) consisted of 22 individuals with UCLP and class III malocclusion. Two subgroups of individuals with class III malocclusion as a result of maxillary retrusion with (UCLP'; n = 19) and without (CON'; n = 8) clefts were also assessed. Interventions Pharyngeal volume, pharyngeal minimal cross-sectional area (CSA), location of CSA, pharyngeal length, sella-nasion-A point angle (SNA), sella-nasion-B point angle (SNB), and A point-nasion-B point angle (ANB), and body mass index were assessed using Dolphin software. Main Outcome Measure The pharyngeal dimensions of UCLP individuals are smaller when compared with controls. Results Mean pharyngeal volume (standard deviation) for the UCLP patients (20.8 [3.9] cm3) and the UCLP’ patients (20.3 [3.9] cm3) were significantly decreased when compared with the CON (28.2 [10.0] cm3) and CON’ patients (29.1 [10.2] cm3), respectively. No differences were found in the pharyngeal minimal CSA, ANB, or pharyngeal length values between groups (CON versus UCLP and CON’ versus UCLP'). CSAs were located mostly at the oropharynx, except in the UCLP’ patients, which were mainly at the hypopharynx. Mean SNA in the UCLP (76.4° [4.6°]) and UCLP’ groups (75.1 [3.1°]) were significantly smaller than those in the CON (82.8° [4.1°]) and CON’ groups (78.6° [1.2°]). SNB values were statistically smaller only for the comparison of CON versus UCLP patients. Conclusion The pharynx of individuals with UCLP and class III malocclusion is volumetrically smaller than that of individuals with class III malocclusion and no clefts.</description><identifier>ISSN: 1055-6656</identifier><identifier>EISSN: 1545-1569</identifier><identifier>DOI: 10.1597/15-124</identifier><identifier>PMID: 27148639</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Adolescent ; Adult ; Birth defects ; Body mass index ; Cleft Lip - diagnostic imaging ; Cleft Palate - diagnostic imaging ; Cone-Beam Computed Tomography ; Cross-Sectional Studies ; Dental occlusion ; Dentistry ; Dimensional analysis ; Female ; Humans ; Hypotheses ; Male ; Malocclusion, Angle Class III - diagnostic imaging ; Medical imaging ; Middle Aged ; Pharynx - anatomy &amp; histology ; Pharynx - diagnostic imaging ; Plastic surgery ; Prospective Studies ; Sleep apnea ; Studies ; Tomography</subject><ispartof>The Cleft palate-craniofacial journal, 2017-09, Vol.54 (5), p.502-508</ispartof><rights>2017 American Cleft Palate-Craniofacial Association</rights><rights>Copyright Allen Press Publishing Services Sep 2017</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c335t-b35c56f2605b0edd89d67975f413b7d49491a46c8e4e2b8cc67c16dc0776e9ab3</citedby><cites>FETCH-LOGICAL-c335t-b35c56f2605b0edd89d67975f413b7d49491a46c8e4e2b8cc67c16dc0776e9ab3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1597/15-124$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1597/15-124$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21798,27901,27902,43597,43598</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27148639$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ivy Kiemle, Trindade-Suedam</creatorcontrib><creatorcontrib>Thiago, Freire Lima</creatorcontrib><creatorcontrib>Letícia, Dominguez Campos</creatorcontrib><creatorcontrib>Renato Yassutaka, Faria Yaedú</creatorcontrib><creatorcontrib>Hugo Nary, Filho</creatorcontrib><creatorcontrib>Inge Elly, Kiemle Trindade</creatorcontrib><title>Tomographic Pharyngeal Dimensions in Individuals with Unilateral Cleft Lip/Palate and Class III Malocclusion are Reduced When Compared with Controls</title><title>The Cleft palate-craniofacial journal</title><addtitle>Cleft Palate Craniofac J</addtitle><description>Objective The objective of this study was to three-dimensionally evaluate the pharyngeal dimensions of individuals with complete nonsyndromic unilateral cleft lip and palate (UCLP) using cone beam computed tomography. Design This was a cross-sectional prospective study. Setting The study took place at the Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru-SP, Brazil. Patients and Participants The control group (CON) consisted of 23 noncleft adults with class III malocclusion, and the cleft group (UCLP) consisted of 22 individuals with UCLP and class III malocclusion. Two subgroups of individuals with class III malocclusion as a result of maxillary retrusion with (UCLP'; n = 19) and without (CON'; n = 8) clefts were also assessed. Interventions Pharyngeal volume, pharyngeal minimal cross-sectional area (CSA), location of CSA, pharyngeal length, sella-nasion-A point angle (SNA), sella-nasion-B point angle (SNB), and A point-nasion-B point angle (ANB), and body mass index were assessed using Dolphin software. Main Outcome Measure The pharyngeal dimensions of UCLP individuals are smaller when compared with controls. Results Mean pharyngeal volume (standard deviation) for the UCLP patients (20.8 [3.9] cm3) and the UCLP’ patients (20.3 [3.9] cm3) were significantly decreased when compared with the CON (28.2 [10.0] cm3) and CON’ patients (29.1 [10.2] cm3), respectively. No differences were found in the pharyngeal minimal CSA, ANB, or pharyngeal length values between groups (CON versus UCLP and CON’ versus UCLP'). CSAs were located mostly at the oropharynx, except in the UCLP’ patients, which were mainly at the hypopharynx. Mean SNA in the UCLP (76.4° [4.6°]) and UCLP’ groups (75.1 [3.1°]) were significantly smaller than those in the CON (82.8° [4.1°]) and CON’ groups (78.6° [1.2°]). SNB values were statistically smaller only for the comparison of CON versus UCLP patients. Conclusion The pharynx of individuals with UCLP and class III malocclusion is volumetrically smaller than that of individuals with class III malocclusion and no clefts.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Birth defects</subject><subject>Body mass index</subject><subject>Cleft Lip - diagnostic imaging</subject><subject>Cleft Palate - diagnostic imaging</subject><subject>Cone-Beam Computed Tomography</subject><subject>Cross-Sectional Studies</subject><subject>Dental occlusion</subject><subject>Dentistry</subject><subject>Dimensional analysis</subject><subject>Female</subject><subject>Humans</subject><subject>Hypotheses</subject><subject>Male</subject><subject>Malocclusion, Angle Class III - diagnostic imaging</subject><subject>Medical imaging</subject><subject>Middle Aged</subject><subject>Pharynx - anatomy &amp; histology</subject><subject>Pharynx - diagnostic imaging</subject><subject>Plastic surgery</subject><subject>Prospective Studies</subject><subject>Sleep apnea</subject><subject>Studies</subject><subject>Tomography</subject><issn>1055-6656</issn><issn>1545-1569</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNpdkW9r1TAUxoM43Jz6ESQgiG_qkjZJm5fSOS3c4ZANX5Y0Ob03I01q0ir7Hn5gc7nb_PPmnMPDj-cJeRB6Rcl7ymV9RnlBS_YEnVDO8smFfJpvwnkhBBfH6HlKt4SUnJbNM3Rc1pQ1opIn6Nd1mMI2qnlnNb7aqXjnt6AcPrcT-GSDT9h63Hljf1izKpfwT7vs8I23Ti0QM9k6GBe8sfPZldprWHmTRZUS7roOXyoXtHbr3gurCPgrmFWDwd924HEbpjmL5uDaBr_E4NILdDTmKHh5v0_RzcXH6_ZzsfnyqWs_bApdVXwphoprLsZSED4QMKaRRtSy5iOj1VAbJpmkigndAINyaLQWtabCaFLXAqQaqlP07uA7x_B9hbT0k00anFMewpp62pRCZJiSjL75D70Na_T5dT2VpRSSE1Zl6u2B0jGkFGHs52in_Kk9Jf2-pzz63FMGX9_brcME5hF7KOZPXlJb-CvrX5vf0fKYiA</recordid><startdate>201709</startdate><enddate>201709</enddate><creator>Ivy Kiemle, Trindade-Suedam</creator><creator>Thiago, Freire Lima</creator><creator>Letícia, Dominguez Campos</creator><creator>Renato Yassutaka, Faria Yaedú</creator><creator>Hugo Nary, Filho</creator><creator>Inge Elly, Kiemle Trindade</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88G</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8FQ</scope><scope>8FV</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M3G</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>201709</creationdate><title>Tomographic Pharyngeal Dimensions in Individuals with Unilateral Cleft Lip/Palate and Class III Malocclusion are Reduced When Compared with Controls</title><author>Ivy Kiemle, Trindade-Suedam ; 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Design This was a cross-sectional prospective study. Setting The study took place at the Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru-SP, Brazil. Patients and Participants The control group (CON) consisted of 23 noncleft adults with class III malocclusion, and the cleft group (UCLP) consisted of 22 individuals with UCLP and class III malocclusion. Two subgroups of individuals with class III malocclusion as a result of maxillary retrusion with (UCLP'; n = 19) and without (CON'; n = 8) clefts were also assessed. Interventions Pharyngeal volume, pharyngeal minimal cross-sectional area (CSA), location of CSA, pharyngeal length, sella-nasion-A point angle (SNA), sella-nasion-B point angle (SNB), and A point-nasion-B point angle (ANB), and body mass index were assessed using Dolphin software. Main Outcome Measure The pharyngeal dimensions of UCLP individuals are smaller when compared with controls. Results Mean pharyngeal volume (standard deviation) for the UCLP patients (20.8 [3.9] cm3) and the UCLP’ patients (20.3 [3.9] cm3) were significantly decreased when compared with the CON (28.2 [10.0] cm3) and CON’ patients (29.1 [10.2] cm3), respectively. No differences were found in the pharyngeal minimal CSA, ANB, or pharyngeal length values between groups (CON versus UCLP and CON’ versus UCLP'). CSAs were located mostly at the oropharynx, except in the UCLP’ patients, which were mainly at the hypopharynx. Mean SNA in the UCLP (76.4° [4.6°]) and UCLP’ groups (75.1 [3.1°]) were significantly smaller than those in the CON (82.8° [4.1°]) and CON’ groups (78.6° [1.2°]). SNB values were statistically smaller only for the comparison of CON versus UCLP patients. Conclusion The pharynx of individuals with UCLP and class III malocclusion is volumetrically smaller than that of individuals with class III malocclusion and no clefts.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>27148639</pmid><doi>10.1597/15-124</doi><tpages>7</tpages></addata></record>
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1545-1569
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source MEDLINE; SAGE Complete
subjects Adolescent
Adult
Birth defects
Body mass index
Cleft Lip - diagnostic imaging
Cleft Palate - diagnostic imaging
Cone-Beam Computed Tomography
Cross-Sectional Studies
Dental occlusion
Dentistry
Dimensional analysis
Female
Humans
Hypotheses
Male
Malocclusion, Angle Class III - diagnostic imaging
Medical imaging
Middle Aged
Pharynx - anatomy & histology
Pharynx - diagnostic imaging
Plastic surgery
Prospective Studies
Sleep apnea
Studies
Tomography
title Tomographic Pharyngeal Dimensions in Individuals with Unilateral Cleft Lip/Palate and Class III Malocclusion are Reduced When Compared with Controls
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