Bovine herpesvirus 4-based vector delivering a hybrid rat/human HER-2 oncoantigen efficiently protects mice from autochthonous Her-2+ mammary cancer

The epidermal growth factor receptor 2 (HER-2) oncogene is a major target for the immunotherapy of breast cancer. Following up to the therapeutic success achieved with Her-2-targeting monoclonal antibodies, immune-prophylactic approaches directed against Her-2 have also been investigated taking into...

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Veröffentlicht in:	Oncoimmunology 2016-03, Vol.5 (3), p.e1082705-e1082705
Hauptverfasser:	Jacca, Sarah, Rolih, Valeria, Quaglino, Elena, Franceschi, Valentina, Tebaldi, Giulia, Bolli, Elisabetta, Rosamilia, Alfonso, Ottonello, Simone, Cavallo, Federica, Donofrio, Gaetano
Format:	Artikel
Sprache:	eng
Schlagworte:	BALB-neuT mice BoHV-4-based vector HER-2 antibodies Her-2 oncogene Original Research recombinant BoHV-4s vaccination
Online-Zugang:	Volltext
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