The protective effects of zinc in lead-induced testicular and epididymal toxicity in Wistar rats

The aim of this study was to investigate the beneficial effects of zinc (Zn) in preventing lead (Pb)-induced reproductive toxicity in Wistar rats. The rats were divided into four groups, namely, control group, Pb group, Zn group, and Pb + Zn group. Animals were exposed to Pb (819 mg of Pb/L) or Zn (...

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Veröffentlicht in:	Toxicology and industrial health 2017-03, Vol.33 (3), p.265-276
Hauptverfasser:	Anjum, M Reshma, Madhu, P, Reddy, K Pratap, Reddy, P Sreenivasula
Format:	Artikel
Sprache:	eng
Schlagworte:	17-Hydroxysteroid Dehydrogenases - antagonists & inhibitors 17-Hydroxysteroid Dehydrogenases - chemistry 17-Hydroxysteroid Dehydrogenases - metabolism 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors 3-Hydroxysteroid Dehydrogenases - chemistry 3-Hydroxysteroid Dehydrogenases - metabolism Animals Biomarkers - blood Biomarkers - metabolism Catalase Dietary Supplements - adverse effects Drinking water Epididymis Epididymis - drug effects Epididymis - metabolism Epididymis - pathology Exposure Hydroxysteroids Infertility, Male - etiology Infertility, Male - prevention & control Lead Lead Poisoning - metabolism Lead Poisoning - pathology Lead Poisoning - physiopathology Lead Poisoning - prevention & control Lipid peroxidation Lipid Peroxidation - drug effects Lipids Lumens Male Organ Size - drug effects Organometallic Compounds - antagonists & inhibitors Organometallic Compounds - toxicity Organs Oxidative stress Oxidative Stress - drug effects Peroxidation Protective Agents - adverse effects Protective Agents - therapeutic use Random Allocation Rats, Wistar Rodents Sperm Spermatogenesis Spermatogenesis - drug effects Spermatozoa - drug effects Spermatozoa - pathology Steroidogenesis Superoxide dismutase Supplements Testes Testis - drug effects Testis - metabolism Testis - pathology Testosterone Testosterone - blood Toxicity Waterborne Diseases - metabolism Waterborne Diseases - pathology Waterborne Diseases - physiopathology Waterborne Diseases - prevention & control Zinc Zinc - adverse effects Zinc - therapeutic use
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