The functional capacity and quality of life of women with advanced breast cancer
Background The rehabilitation needs of patients with metastatic breast cancer (MBC) are poorly studied. The primary aim of the study was to evaluate the functional capacity of women with MBC and quality of life (QoL). Methods The present study is an open, non-randomized, prospective cross-sectional...
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| Veröffentlicht in: | Breast cancer (Tokyo, Japan) Japan), 2017, Vol.24 (1), p.128-136 |
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| creator | Kokkonen, K. Saarto, T. Mäkinen, T. Pohjola, L. Kautio, H. Järvenpää, S. Puustjärvi-Sunabacka, K. |
| description | Background
The rehabilitation needs of patients with metastatic breast cancer (MBC) are poorly studied. The primary aim of the study was to evaluate the functional capacity of women with MBC and quality of life (QoL).
Methods
The present study is an open, non-randomized, prospective cross-sectional observation study. The functional capacity of 128 MBC patients with ongoing cancer treatments, were studied in Helsinki University Hospital (HUS): Peak expiratory flow (PEF), dynamic and static balance, 6 minute walking distance (6MWD), 10 meter walking, sit-to-stand test, repeated squat, grip strength, shoulder movement, pain, and QoL by Beck’s depression scale (BDI), health assessment questionnaire (HAQ), RAND SF-36 and EORTC QLQ-30 items.
Results
The walking capacity was compromised in half and the strength of the lower extremities in one-third of the patients. PEF was below the normal reference in 55 %, static balance in 62 % and dynamic balance in 73 % (≤60 year olds) and 81 % (≥61 year olds). The grip power was lowered in 44/30 % of the patients (right/left) and the shoulder movement was restricted in 30 %. Some disability in physical functioning experienced 55 % (HAQ) and 37 % felt depressive (BDI). The QoL (RAND SF-36) was poor especially in the field of physical, role and social functioning and bodily pain ( |
| doi_str_mv | 10.1007/s12282-016-0687-2 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1826667054</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A712279961</galeid><sourcerecordid>A712279961</sourcerecordid><originalsourceid>FETCH-LOGICAL-c478t-98a112eb2cbf9e785170e5d0d2a13f4376ddc932ef087c20e8b5868538bfbcaa3</originalsourceid><addsrcrecordid>eNp9kUFLHjEQhkOxVGv7A7zIghcvayfZ3SR7FFFbENqDPYdsMtHIbvKZ7Cr--2ZZLQil5DCTyfMOk3kJOaJwRgHEt0wZk6wGymvgUtTsAzmgUkLdsqbZK3nTQs0ll_vkc84PAG0jgH8i-0wAsF7KA_Lr9h4rtwQz-xj0WBm908bPL5UOtnpc9Ljm0VWjd7jG5zhhqJ79fF9p-6SDQVsNCXWei7Tc0hfy0ekx49fXeEh-X13eXnyvb35e_7g4v6lNK-Rc91JTynBgZnA9CtlRAdhZsEzTxpU5ubWmbxg6kMIwQDl05SNdIwc3GK2bQ3K69d2l-LhgntXks8Fx1AHjkhWVjHMuoGsLerKhd3pE5YOLc9JmxdW5KCsUfc9poc7-QZVjcfImBnS-1N8J6CYwKeac0Kld8pNOL4qCWv1Rmz-q-KNWfxQrmuPXqZdhQvtX8WZIAdgG5PIU7jCph7ik4kz-T9c_BnyZUA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1826667054</pqid></control><display><type>article</type><title>The functional capacity and quality of life of women with advanced breast cancer</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Kokkonen, K. ; Saarto, T. ; Mäkinen, T. ; Pohjola, L. ; Kautio, H. ; Järvenpää, S. ; Puustjärvi-Sunabacka, K.</creator><creatorcontrib>Kokkonen, K. ; Saarto, T. ; Mäkinen, T. ; Pohjola, L. ; Kautio, H. ; Järvenpää, S. ; Puustjärvi-Sunabacka, K.</creatorcontrib><description>Background
The rehabilitation needs of patients with metastatic breast cancer (MBC) are poorly studied. The primary aim of the study was to evaluate the functional capacity of women with MBC and quality of life (QoL).
Methods
The present study is an open, non-randomized, prospective cross-sectional observation study. The functional capacity of 128 MBC patients with ongoing cancer treatments, were studied in Helsinki University Hospital (HUS): Peak expiratory flow (PEF), dynamic and static balance, 6 minute walking distance (6MWD), 10 meter walking, sit-to-stand test, repeated squat, grip strength, shoulder movement, pain, and QoL by Beck’s depression scale (BDI), health assessment questionnaire (HAQ), RAND SF-36 and EORTC QLQ-30 items.
Results
The walking capacity was compromised in half and the strength of the lower extremities in one-third of the patients. PEF was below the normal reference in 55 %, static balance in 62 % and dynamic balance in 73 % (≤60 year olds) and 81 % (≥61 year olds). The grip power was lowered in 44/30 % of the patients (right/left) and the shoulder movement was restricted in 30 %. Some disability in physical functioning experienced 55 % (HAQ) and 37 % felt depressive (BDI). The QoL (RAND SF-36) was poor especially in the field of physical, role and social functioning and bodily pain (<0.001). Pain, depression, and a poor 6MWD results independently determined the physical component of QoL (
p
< 0.001).
Conclusions
The functional capacity of patients with MBC was significantly lowered. This, in association with distressing symptoms like pain and depression causes a vicious circle further leading to functional disabilities and impaired QoL.</description><identifier>ISSN: 1340-6868</identifier><identifier>EISSN: 1880-4233</identifier><identifier>DOI: 10.1007/s12282-016-0687-2</identifier><identifier>PMID: 27002988</identifier><language>eng</language><publisher>Tokyo: Springer Japan</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Body Mass Index ; Breast cancer ; Breast Neoplasms - complications ; Breast Neoplasms - drug therapy ; Breast Neoplasms - pathology ; Cancer ; Cancer Research ; Care and treatment ; Cross-Sectional Studies ; Depression - etiology ; Depression, Mental ; Exercise ; Female ; Humans ; Medicine ; Medicine & Public Health ; Metastasis ; Middle Aged ; Oncology ; Oncology, Experimental ; Original Article ; Pain - etiology ; Prospective Studies ; Quality of Life ; Surgery ; Surgical Oncology ; Surveys ; Surveys and Questionnaires ; Walking ; Women</subject><ispartof>Breast cancer (Tokyo, Japan), 2017, Vol.24 (1), p.128-136</ispartof><rights>The Japanese Breast Cancer Society 2016</rights><rights>COPYRIGHT 2017 Springer</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c478t-98a112eb2cbf9e785170e5d0d2a13f4376ddc932ef087c20e8b5868538bfbcaa3</citedby><cites>FETCH-LOGICAL-c478t-98a112eb2cbf9e785170e5d0d2a13f4376ddc932ef087c20e8b5868538bfbcaa3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s12282-016-0687-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s12282-016-0687-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27002988$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kokkonen, K.</creatorcontrib><creatorcontrib>Saarto, T.</creatorcontrib><creatorcontrib>Mäkinen, T.</creatorcontrib><creatorcontrib>Pohjola, L.</creatorcontrib><creatorcontrib>Kautio, H.</creatorcontrib><creatorcontrib>Järvenpää, S.</creatorcontrib><creatorcontrib>Puustjärvi-Sunabacka, K.</creatorcontrib><title>The functional capacity and quality of life of women with advanced breast cancer</title><title>Breast cancer (Tokyo, Japan)</title><addtitle>Breast Cancer</addtitle><addtitle>Breast Cancer</addtitle><description>Background
The rehabilitation needs of patients with metastatic breast cancer (MBC) are poorly studied. The primary aim of the study was to evaluate the functional capacity of women with MBC and quality of life (QoL).
Methods
The present study is an open, non-randomized, prospective cross-sectional observation study. The functional capacity of 128 MBC patients with ongoing cancer treatments, were studied in Helsinki University Hospital (HUS): Peak expiratory flow (PEF), dynamic and static balance, 6 minute walking distance (6MWD), 10 meter walking, sit-to-stand test, repeated squat, grip strength, shoulder movement, pain, and QoL by Beck’s depression scale (BDI), health assessment questionnaire (HAQ), RAND SF-36 and EORTC QLQ-30 items.
Results
The walking capacity was compromised in half and the strength of the lower extremities in one-third of the patients. PEF was below the normal reference in 55 %, static balance in 62 % and dynamic balance in 73 % (≤60 year olds) and 81 % (≥61 year olds). The grip power was lowered in 44/30 % of the patients (right/left) and the shoulder movement was restricted in 30 %. Some disability in physical functioning experienced 55 % (HAQ) and 37 % felt depressive (BDI). The QoL (RAND SF-36) was poor especially in the field of physical, role and social functioning and bodily pain (<0.001). Pain, depression, and a poor 6MWD results independently determined the physical component of QoL (
p
< 0.001).
Conclusions
The functional capacity of patients with MBC was significantly lowered. This, in association with distressing symptoms like pain and depression causes a vicious circle further leading to functional disabilities and impaired QoL.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Body Mass Index</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - complications</subject><subject>Breast Neoplasms - drug therapy</subject><subject>Breast Neoplasms - pathology</subject><subject>Cancer</subject><subject>Cancer Research</subject><subject>Care and treatment</subject><subject>Cross-Sectional Studies</subject><subject>Depression - etiology</subject><subject>Depression, Mental</subject><subject>Exercise</subject><subject>Female</subject><subject>Humans</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Metastasis</subject><subject>Middle Aged</subject><subject>Oncology</subject><subject>Oncology, Experimental</subject><subject>Original Article</subject><subject>Pain - etiology</subject><subject>Prospective Studies</subject><subject>Quality of Life</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><subject>Surveys</subject><subject>Surveys and Questionnaires</subject><subject>Walking</subject><subject>Women</subject><issn>1340-6868</issn><issn>1880-4233</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUFLHjEQhkOxVGv7A7zIghcvayfZ3SR7FFFbENqDPYdsMtHIbvKZ7Cr--2ZZLQil5DCTyfMOk3kJOaJwRgHEt0wZk6wGymvgUtTsAzmgUkLdsqbZK3nTQs0ll_vkc84PAG0jgH8i-0wAsF7KA_Lr9h4rtwQz-xj0WBm908bPL5UOtnpc9Ljm0VWjd7jG5zhhqJ79fF9p-6SDQVsNCXWei7Tc0hfy0ekx49fXeEh-X13eXnyvb35e_7g4v6lNK-Rc91JTynBgZnA9CtlRAdhZsEzTxpU5ubWmbxg6kMIwQDl05SNdIwc3GK2bQ3K69d2l-LhgntXks8Fx1AHjkhWVjHMuoGsLerKhd3pE5YOLc9JmxdW5KCsUfc9poc7-QZVjcfImBnS-1N8J6CYwKeac0Kld8pNOL4qCWv1Rmz-q-KNWfxQrmuPXqZdhQvtX8WZIAdgG5PIU7jCph7ik4kz-T9c_BnyZUA</recordid><startdate>2017</startdate><enddate>2017</enddate><creator>Kokkonen, K.</creator><creator>Saarto, T.</creator><creator>Mäkinen, T.</creator><creator>Pohjola, L.</creator><creator>Kautio, H.</creator><creator>Järvenpää, S.</creator><creator>Puustjärvi-Sunabacka, K.</creator><general>Springer Japan</general><general>Springer</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2017</creationdate><title>The functional capacity and quality of life of women with advanced breast cancer</title><author>Kokkonen, K. ; Saarto, T. ; Mäkinen, T. ; Pohjola, L. ; Kautio, H. ; Järvenpää, S. ; Puustjärvi-Sunabacka, K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c478t-98a112eb2cbf9e785170e5d0d2a13f4376ddc932ef087c20e8b5868538bfbcaa3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Body Mass Index</topic><topic>Breast cancer</topic><topic>Breast Neoplasms - complications</topic><topic>Breast Neoplasms - drug therapy</topic><topic>Breast Neoplasms - pathology</topic><topic>Cancer</topic><topic>Cancer Research</topic><topic>Care and treatment</topic><topic>Cross-Sectional Studies</topic><topic>Depression - etiology</topic><topic>Depression, Mental</topic><topic>Exercise</topic><topic>Female</topic><topic>Humans</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Metastasis</topic><topic>Middle Aged</topic><topic>Oncology</topic><topic>Oncology, Experimental</topic><topic>Original Article</topic><topic>Pain - etiology</topic><topic>Prospective Studies</topic><topic>Quality of Life</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><topic>Surveys</topic><topic>Surveys and Questionnaires</topic><topic>Walking</topic><topic>Women</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kokkonen, K.</creatorcontrib><creatorcontrib>Saarto, T.</creatorcontrib><creatorcontrib>Mäkinen, T.</creatorcontrib><creatorcontrib>Pohjola, L.</creatorcontrib><creatorcontrib>Kautio, H.</creatorcontrib><creatorcontrib>Järvenpää, S.</creatorcontrib><creatorcontrib>Puustjärvi-Sunabacka, K.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Breast cancer (Tokyo, Japan)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kokkonen, K.</au><au>Saarto, T.</au><au>Mäkinen, T.</au><au>Pohjola, L.</au><au>Kautio, H.</au><au>Järvenpää, S.</au><au>Puustjärvi-Sunabacka, K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The functional capacity and quality of life of women with advanced breast cancer</atitle><jtitle>Breast cancer (Tokyo, Japan)</jtitle><stitle>Breast Cancer</stitle><addtitle>Breast Cancer</addtitle><date>2017</date><risdate>2017</risdate><volume>24</volume><issue>1</issue><spage>128</spage><epage>136</epage><pages>128-136</pages><issn>1340-6868</issn><eissn>1880-4233</eissn><abstract>Background
The rehabilitation needs of patients with metastatic breast cancer (MBC) are poorly studied. The primary aim of the study was to evaluate the functional capacity of women with MBC and quality of life (QoL).
Methods
The present study is an open, non-randomized, prospective cross-sectional observation study. The functional capacity of 128 MBC patients with ongoing cancer treatments, were studied in Helsinki University Hospital (HUS): Peak expiratory flow (PEF), dynamic and static balance, 6 minute walking distance (6MWD), 10 meter walking, sit-to-stand test, repeated squat, grip strength, shoulder movement, pain, and QoL by Beck’s depression scale (BDI), health assessment questionnaire (HAQ), RAND SF-36 and EORTC QLQ-30 items.
Results
The walking capacity was compromised in half and the strength of the lower extremities in one-third of the patients. PEF was below the normal reference in 55 %, static balance in 62 % and dynamic balance in 73 % (≤60 year olds) and 81 % (≥61 year olds). The grip power was lowered in 44/30 % of the patients (right/left) and the shoulder movement was restricted in 30 %. Some disability in physical functioning experienced 55 % (HAQ) and 37 % felt depressive (BDI). The QoL (RAND SF-36) was poor especially in the field of physical, role and social functioning and bodily pain (<0.001). Pain, depression, and a poor 6MWD results independently determined the physical component of QoL (
p
< 0.001).
Conclusions
The functional capacity of patients with MBC was significantly lowered. This, in association with distressing symptoms like pain and depression causes a vicious circle further leading to functional disabilities and impaired QoL.</abstract><cop>Tokyo</cop><pub>Springer Japan</pub><pmid>27002988</pmid><doi>10.1007/s12282-016-0687-2</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Adult Aged Aged, 80 and over Body Mass Index Breast cancer Breast Neoplasms - complications Breast Neoplasms - drug therapy Breast Neoplasms - pathology Cancer Cancer Research Care and treatment Cross-Sectional Studies Depression - etiology Depression, Mental Exercise Female Humans Medicine Medicine & Public Health Metastasis Middle Aged Oncology Oncology, Experimental Original Article Pain - etiology Prospective Studies Quality of Life Surgery Surgical Oncology Surveys Surveys and Questionnaires Walking Women |
| title | The functional capacity and quality of life of women with advanced breast cancer |
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