Elective neck management for squamous cell carcinoma metastatic to the parotid area lymph nodes
The objective of this study is to determine if radiotherapy (RT) alone to the cervical lymphatics is a suitable alternative to elective neck dissection (END) in patients who undergo parotidectomy and postoperative RT for squamous cell carcinoma metastatic to the parotid area lymph nodes (PALN). We r...
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| Veröffentlicht in: | European archives of oto-rhino-laryngology 2016-11, Vol.273 (11), p.3875-3879 |
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| container_title | European archives of oto-rhino-laryngology |
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| creator | Herman, Michael P. Amdur, Robert J. Werning, John W. Dziegielewski, Peter Morris, Christopher G. Mendenhall, William M. |
| description | The objective of this study is to determine if radiotherapy (RT) alone to the cervical lymphatics is a suitable alternative to elective neck dissection (END) in patients who undergo parotidectomy and postoperative RT for squamous cell carcinoma metastatic to the parotid area lymph nodes (PALN). We retrospectively reviewed the medical records of 107 patients consecutively treated from November 1969 to March 2012 for cutaneous squamous cell carcinoma metastatic to the PALN with a clinically node-negative neck. Primary therapy consisted of parotidectomy in all cases. We compared regional (cervical) control in two subgroups: 42 patients treated with END and RT and 65 patients treated with elective neck irradiation (ENI) alone. The median time of follow-up was 5.5 years (range 0.3–30 years) for all patients and 11 years for living patients (range 1.8–26 years). There was 1 neck recurrence in each subgroup: END and RT, 1/42 (2 %); and ENI alone, 1/65 (1.5 %). No patient experienced a complication related to neck RT. ENI to a dose of approximately 50–60 Gy is a suitable alternative to END and postoperative RT in patients with squamous cell carcinoma metastatic to the PALN. |
| doi_str_mv | 10.1007/s00405-016-4021-6 |
| format | Article |
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We retrospectively reviewed the medical records of 107 patients consecutively treated from November 1969 to March 2012 for cutaneous squamous cell carcinoma metastatic to the PALN with a clinically node-negative neck. Primary therapy consisted of parotidectomy in all cases. We compared regional (cervical) control in two subgroups: 42 patients treated with END and RT and 65 patients treated with elective neck irradiation (ENI) alone. The median time of follow-up was 5.5 years (range 0.3–30 years) for all patients and 11 years for living patients (range 1.8–26 years). There was 1 neck recurrence in each subgroup: END and RT, 1/42 (2 %); and ENI alone, 1/65 (1.5 %). No patient experienced a complication related to neck RT. ENI to a dose of approximately 50–60 Gy is a suitable alternative to END and postoperative RT in patients with squamous cell carcinoma metastatic to the PALN.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Carcinoma, Squamous Cell - radiotherapy</subject><subject>Carcinoma, Squamous Cell - secondary</subject><subject>Carcinoma, Squamous Cell - surgery</subject><subject>Disease Management</subject><subject>Elective Surgical Procedures</subject><subject>Female</subject><subject>Head and Neck</subject><subject>Head and Neck Surgery</subject><subject>Humans</subject><subject>Lymph Nodes - pathology</subject><subject>Lymphatic Metastasis</subject><subject>Male</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Middle Aged</subject><subject>Neck Dissection</subject><subject>Neoplasm Staging</subject><subject>Neurosurgery</subject><subject>Otorhinolaryngology</subject><subject>Parotid Neoplasms - radiotherapy</subject><subject>Parotid Neoplasms - secondary</subject><subject>Parotid Neoplasms - surgery</subject><subject>Retrospective Studies</subject><subject>Skin Neoplasms - pathology</subject><issn>0937-4477</issn><issn>1434-4726</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kLtOxDAQRS0EguXxATTIJU3Aj4mzKRHiJa1EA7U1cWbZLHG82A4Sf09WC5RUU8yZq7mHsXMprqQQ1XUSAkRZCGkKEEoWZo_NJGgooFJmn81ErasCoKqO2HFKayFECbU-ZEeqEjAvlZwxe9eTy90n8YHcO_c44Bt5GjJfhsjTx4g-jIk76nvuMLpuCB65p4wpY-4cz4HnFfENxpC7lmMk5P2X36z4EFpKp-xgiX2is595wl7v715uH4vF88PT7c2icBogF6iNlGhUWxuNaJqmBddIUqVq5g3UBkBphW1dOiWNkk1lKtcujdbOIdBU6oRd7nI3MXyMlLL1Xdp-jQNNBaycK2MMSAETKneoiyGlSEu7iZ3H-GWlsFuvdufVTl7t1qs1083FT_zYeGr_Ln5FToDaAWlaDW8U7TqMcZgq_5P6Dd9Cg3M</recordid><startdate>20161101</startdate><enddate>20161101</enddate><creator>Herman, Michael P.</creator><creator>Amdur, Robert J.</creator><creator>Werning, John W.</creator><creator>Dziegielewski, Peter</creator><creator>Morris, Christopher G.</creator><creator>Mendenhall, William M.</creator><general>Springer Berlin Heidelberg</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20161101</creationdate><title>Elective neck management for squamous cell carcinoma metastatic to the parotid area lymph nodes</title><author>Herman, Michael P. ; 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We retrospectively reviewed the medical records of 107 patients consecutively treated from November 1969 to March 2012 for cutaneous squamous cell carcinoma metastatic to the PALN with a clinically node-negative neck. Primary therapy consisted of parotidectomy in all cases. We compared regional (cervical) control in two subgroups: 42 patients treated with END and RT and 65 patients treated with elective neck irradiation (ENI) alone. The median time of follow-up was 5.5 years (range 0.3–30 years) for all patients and 11 years for living patients (range 1.8–26 years). There was 1 neck recurrence in each subgroup: END and RT, 1/42 (2 %); and ENI alone, 1/65 (1.5 %). No patient experienced a complication related to neck RT. 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| subjects | Adult Aged Aged, 80 and over Carcinoma, Squamous Cell - radiotherapy Carcinoma, Squamous Cell - secondary Carcinoma, Squamous Cell - surgery Disease Management Elective Surgical Procedures Female Head and Neck Head and Neck Surgery Humans Lymph Nodes - pathology Lymphatic Metastasis Male Medicine Medicine & Public Health Middle Aged Neck Dissection Neoplasm Staging Neurosurgery Otorhinolaryngology Parotid Neoplasms - radiotherapy Parotid Neoplasms - secondary Parotid Neoplasms - surgery Retrospective Studies Skin Neoplasms - pathology |
| title | Elective neck management for squamous cell carcinoma metastatic to the parotid area lymph nodes |
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