Genotype impacts survival in Marfan syndrome

The aorta in Marfan syndrome (MFS) patients is variably affected. We investigated the assumed genotype-effect on protein production as a risk factor for a severe aortic phenotype in adult MFS patients. We collected clinical and genetic data from all 570 adults with MFS who had been included in the D...

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Veröffentlicht in:	European heart journal 2016-11, Vol.37 (43), p.3285-3290
Hauptverfasser:	Franken, Romy, Groenink, Maarten, de Waard, Vivian, Feenstra, Helena M A, Scholte, Arthur J, van den Berg, Maarten P, Pals, Gerard, Zwinderman, Aeilko H, Timmermans, Janneke, Mulder, Barbara J M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Female Fibrillin-1 Fibrillins Genotype Humans Male Marfan Syndrome Microfilament Proteins
Online-Zugang:	Volltext
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