Synthesis of Some 1,4,6-Trisubstituted-2-oxo-1,2-dihydropyridine-3-carbonitriles and Their Biological Evaluation as Cytotoxic and Antimicrobial Agents

A series of novel 1,4,6‐trisubstituted‐2‐oxo‐1,2‐dihydropyridine‐3‐carbonitriles supported with some functionalities reported to contribute to significant chemotherapeutic potential were synthesized and evaluated for their antimicrobial and/or cytotoxic activities. Thirteen compounds exhibited cytot...

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Veröffentlicht in:	Archiv der Pharmazie (Weinheim) 2015-11, Vol.348 (11), p.824-834
Hauptverfasser:	Faidallah, Hassan M., Rostom, Sherif A. F., Badr, Mona H., Ismail, Azza E., Almohammadi, Ameen M.
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3‐Benzodioxole 3-Benzodioxole Antimicrobial Antimicrobial agents Cytotoxic Cytotoxicity Ovarian cancer Pyridines Synthesis
Online-Zugang:	Volltext
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