Sonographic appearance of thyroid glands in patients treated with intensity-modulated radiotherapy or conventional radiotherapy for nasopharyngeal carcinoma
ABSTRACT Background This study aimed to investigate the sonographic appearances of the thyroid glands in nasopharyngeal carcinoma (NPC) patients whose cervical lymph nodes were treated with conventional radiotherapy (RT) or intensity‐modulated radiotherapy (IMRT). The post‐RT sonographic appearances...
Gespeichert in:
| Veröffentlicht in: | Journal of clinical ultrasound 2015-05, Vol.43 (4), p.210-223 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 223 |
|---|---|
| container_issue | 4 |
| container_start_page | 210 |
| container_title | Journal of clinical ultrasound |
| container_volume | 43 |
| creator | Cheng, Sammy C.H. Wu, Vincent W.C. Kwong, Dora L.W. Lui, C.Y. Cheng, Ashley C.K. Kot, Brian C.W. Ying, Michael T.C. |
| description | ABSTRACT
Background
This study aimed to investigate the sonographic appearances of the thyroid glands in nasopharyngeal carcinoma (NPC) patients whose cervical lymph nodes were treated with conventional radiotherapy (RT) or intensity‐modulated radiotherapy (IMRT). The post‐RT sonographic appearances of the thyroid glands in NPC patients were also correlated with the thyroid function.
Methods
One hundred and three NPC patients who had completed RT of cervical lymph nodes using the anterior cervical field, 30 NPC patients who had completed RT of cervical lymph nodes using IMRT, and 61 healthy subjects were included in the study. Thyroid glands were sonographically assessed for their size, echogenicity, vascularity, and internal architecture. Thyroid function tests were also performed on each subject.
Results
In comparison with the patients with abnormal thyroid function, the thyroid glands of the patients with normal thyroid function tended to be homogeneous and to have greater volume and echogenicity index (p |
| doi_str_mv | 10.1002/jcu.22222 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1826598939</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3649181581</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4602-8f30b1ea65f44799022d9369efdc1d5127c937773a51a323d85b7945e62aca573</originalsourceid><addsrcrecordid>eNqFkc1u1DAUhS0EokNhwQsgS2zYpPVPbMdLNGJaqgqEoLC0PI4z8ZCxU9uh5F14WDwzpRJs8OZaOt-50j0HgJcYnWGEyPnWTGdk_x6BBUZSVAhJ_hgsysAVEQyfgGcpbRFCnDH2FJwQhmlTc7YAvz4HHzZRj70zUI-j1VF7Y2HoYO7nGFwLN4P2bYLOw1FnZ31OMEers23hnct9EbL1yeW52oV2Gg5C1K0Lubdl8QxDhCb4H8XpgtfD32JXVK9TGHsdZ7-xRTc6GufDTj8HTzo9JPvifp6Cm9W7L8vL6vrjxfvl2-vK1ByRqukoWmOrOevqWkiJCGkl5dJ2rcEtw0QYSYUQVDOsKaFtw9ZC1sxyoo1mgp6CN8e9Ywy3k01Z7VwydiiH2zAlhRvCmWwklf9HueB0ny4p6Ot_0G2YYgngQGGCBRJ1oV7dU9N6Z1s1RrcrSag_FRXg_AjcucHODzpGat-9Kt2rQ_fqanlz-BRHdXS4lO3PB4eO3xUXVDD17cOF-sS-ri5XcqWu6G-MkbK9</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1671217074</pqid></control><display><type>article</type><title>Sonographic appearance of thyroid glands in patients treated with intensity-modulated radiotherapy or conventional radiotherapy for nasopharyngeal carcinoma</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Cheng, Sammy C.H. ; Wu, Vincent W.C. ; Kwong, Dora L.W. ; Lui, C.Y. ; Cheng, Ashley C.K. ; Kot, Brian C.W. ; Ying, Michael T.C.</creator><creatorcontrib>Cheng, Sammy C.H. ; Wu, Vincent W.C. ; Kwong, Dora L.W. ; Lui, C.Y. ; Cheng, Ashley C.K. ; Kot, Brian C.W. ; Ying, Michael T.C.</creatorcontrib><description>ABSTRACT
Background
This study aimed to investigate the sonographic appearances of the thyroid glands in nasopharyngeal carcinoma (NPC) patients whose cervical lymph nodes were treated with conventional radiotherapy (RT) or intensity‐modulated radiotherapy (IMRT). The post‐RT sonographic appearances of the thyroid glands in NPC patients were also correlated with the thyroid function.
Methods
One hundred and three NPC patients who had completed RT of cervical lymph nodes using the anterior cervical field, 30 NPC patients who had completed RT of cervical lymph nodes using IMRT, and 61 healthy subjects were included in the study. Thyroid glands were sonographically assessed for their size, echogenicity, vascularity, and internal architecture. Thyroid function tests were also performed on each subject.
Results
In comparison with the patients with abnormal thyroid function, the thyroid glands of the patients with normal thyroid function tended to be homogeneous and to have greater volume and echogenicity index (p < 0.05). Compared with those of the healthy subjects, the thyroid glands of patients previously treated with IMRT and those treated with the anterior cervical field showed significantly lower thyroid volume, lower incidence and number of nodules, and higher vascularity index (p < 0.05).
Conclusions
The patient's history of previous RT should be taken into consideration in the sonographic examination of the thyroid gland post‐RT. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound 43:210–223, 2015</description><identifier>ISSN: 0091-2751</identifier><identifier>EISSN: 1097-0096</identifier><identifier>DOI: 10.1002/jcu.22222</identifier><identifier>PMID: 25138465</identifier><identifier>CODEN: JCULDD</identifier><language>eng</language><publisher>United States: Blackwell Publishing Ltd</publisher><subject>hypothyroidism ; nasopharyngeal carcinoma ; radiotherapy ; thyroid ; Ultrasonic imaging ; ultrasonography</subject><ispartof>Journal of clinical ultrasound, 2015-05, Vol.43 (4), p.210-223</ispartof><rights>2014 Wiley Periodicals, Inc.</rights><rights>2015 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4602-8f30b1ea65f44799022d9369efdc1d5127c937773a51a323d85b7945e62aca573</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fjcu.22222$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fjcu.22222$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25138465$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Cheng, Sammy C.H.</creatorcontrib><creatorcontrib>Wu, Vincent W.C.</creatorcontrib><creatorcontrib>Kwong, Dora L.W.</creatorcontrib><creatorcontrib>Lui, C.Y.</creatorcontrib><creatorcontrib>Cheng, Ashley C.K.</creatorcontrib><creatorcontrib>Kot, Brian C.W.</creatorcontrib><creatorcontrib>Ying, Michael T.C.</creatorcontrib><title>Sonographic appearance of thyroid glands in patients treated with intensity-modulated radiotherapy or conventional radiotherapy for nasopharyngeal carcinoma</title><title>Journal of clinical ultrasound</title><addtitle>J. Clin. Ultrasound</addtitle><description>ABSTRACT
Background
This study aimed to investigate the sonographic appearances of the thyroid glands in nasopharyngeal carcinoma (NPC) patients whose cervical lymph nodes were treated with conventional radiotherapy (RT) or intensity‐modulated radiotherapy (IMRT). The post‐RT sonographic appearances of the thyroid glands in NPC patients were also correlated with the thyroid function.
Methods
One hundred and three NPC patients who had completed RT of cervical lymph nodes using the anterior cervical field, 30 NPC patients who had completed RT of cervical lymph nodes using IMRT, and 61 healthy subjects were included in the study. Thyroid glands were sonographically assessed for their size, echogenicity, vascularity, and internal architecture. Thyroid function tests were also performed on each subject.
Results
In comparison with the patients with abnormal thyroid function, the thyroid glands of the patients with normal thyroid function tended to be homogeneous and to have greater volume and echogenicity index (p < 0.05). Compared with those of the healthy subjects, the thyroid glands of patients previously treated with IMRT and those treated with the anterior cervical field showed significantly lower thyroid volume, lower incidence and number of nodules, and higher vascularity index (p < 0.05).
Conclusions
The patient's history of previous RT should be taken into consideration in the sonographic examination of the thyroid gland post‐RT. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound 43:210–223, 2015</description><subject>hypothyroidism</subject><subject>nasopharyngeal carcinoma</subject><subject>radiotherapy</subject><subject>thyroid</subject><subject>Ultrasonic imaging</subject><subject>ultrasonography</subject><issn>0091-2751</issn><issn>1097-0096</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqFkc1u1DAUhS0EokNhwQsgS2zYpPVPbMdLNGJaqgqEoLC0PI4z8ZCxU9uh5F14WDwzpRJs8OZaOt-50j0HgJcYnWGEyPnWTGdk_x6BBUZSVAhJ_hgsysAVEQyfgGcpbRFCnDH2FJwQhmlTc7YAvz4HHzZRj70zUI-j1VF7Y2HoYO7nGFwLN4P2bYLOw1FnZ31OMEers23hnct9EbL1yeW52oV2Gg5C1K0Lubdl8QxDhCb4H8XpgtfD32JXVK9TGHsdZ7-xRTc6GufDTj8HTzo9JPvifp6Cm9W7L8vL6vrjxfvl2-vK1ByRqukoWmOrOevqWkiJCGkl5dJ2rcEtw0QYSYUQVDOsKaFtw9ZC1sxyoo1mgp6CN8e9Ywy3k01Z7VwydiiH2zAlhRvCmWwklf9HueB0ny4p6Ot_0G2YYgngQGGCBRJ1oV7dU9N6Z1s1RrcrSag_FRXg_AjcucHODzpGat-9Kt2rQ_fqanlz-BRHdXS4lO3PB4eO3xUXVDD17cOF-sS-ri5XcqWu6G-MkbK9</recordid><startdate>201505</startdate><enddate>201505</enddate><creator>Cheng, Sammy C.H.</creator><creator>Wu, Vincent W.C.</creator><creator>Kwong, Dora L.W.</creator><creator>Lui, C.Y.</creator><creator>Cheng, Ashley C.K.</creator><creator>Kot, Brian C.W.</creator><creator>Ying, Michael T.C.</creator><general>Blackwell Publishing Ltd</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>NPM</scope><scope>8FD</scope><scope>FR3</scope><scope>K9.</scope><scope>M7Z</scope><scope>P64</scope><scope>7QO</scope><scope>7X8</scope></search><sort><creationdate>201505</creationdate><title>Sonographic appearance of thyroid glands in patients treated with intensity-modulated radiotherapy or conventional radiotherapy for nasopharyngeal carcinoma</title><author>Cheng, Sammy C.H. ; Wu, Vincent W.C. ; Kwong, Dora L.W. ; Lui, C.Y. ; Cheng, Ashley C.K. ; Kot, Brian C.W. ; Ying, Michael T.C.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4602-8f30b1ea65f44799022d9369efdc1d5127c937773a51a323d85b7945e62aca573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>hypothyroidism</topic><topic>nasopharyngeal carcinoma</topic><topic>radiotherapy</topic><topic>thyroid</topic><topic>Ultrasonic imaging</topic><topic>ultrasonography</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cheng, Sammy C.H.</creatorcontrib><creatorcontrib>Wu, Vincent W.C.</creatorcontrib><creatorcontrib>Kwong, Dora L.W.</creatorcontrib><creatorcontrib>Lui, C.Y.</creatorcontrib><creatorcontrib>Cheng, Ashley C.K.</creatorcontrib><creatorcontrib>Kot, Brian C.W.</creatorcontrib><creatorcontrib>Ying, Michael T.C.</creatorcontrib><collection>Istex</collection><collection>PubMed</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biochemistry Abstracts 1</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of clinical ultrasound</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cheng, Sammy C.H.</au><au>Wu, Vincent W.C.</au><au>Kwong, Dora L.W.</au><au>Lui, C.Y.</au><au>Cheng, Ashley C.K.</au><au>Kot, Brian C.W.</au><au>Ying, Michael T.C.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sonographic appearance of thyroid glands in patients treated with intensity-modulated radiotherapy or conventional radiotherapy for nasopharyngeal carcinoma</atitle><jtitle>Journal of clinical ultrasound</jtitle><addtitle>J. Clin. Ultrasound</addtitle><date>2015-05</date><risdate>2015</risdate><volume>43</volume><issue>4</issue><spage>210</spage><epage>223</epage><pages>210-223</pages><issn>0091-2751</issn><eissn>1097-0096</eissn><coden>JCULDD</coden><abstract>ABSTRACT
Background
This study aimed to investigate the sonographic appearances of the thyroid glands in nasopharyngeal carcinoma (NPC) patients whose cervical lymph nodes were treated with conventional radiotherapy (RT) or intensity‐modulated radiotherapy (IMRT). The post‐RT sonographic appearances of the thyroid glands in NPC patients were also correlated with the thyroid function.
Methods
One hundred and three NPC patients who had completed RT of cervical lymph nodes using the anterior cervical field, 30 NPC patients who had completed RT of cervical lymph nodes using IMRT, and 61 healthy subjects were included in the study. Thyroid glands were sonographically assessed for their size, echogenicity, vascularity, and internal architecture. Thyroid function tests were also performed on each subject.
Results
In comparison with the patients with abnormal thyroid function, the thyroid glands of the patients with normal thyroid function tended to be homogeneous and to have greater volume and echogenicity index (p < 0.05). Compared with those of the healthy subjects, the thyroid glands of patients previously treated with IMRT and those treated with the anterior cervical field showed significantly lower thyroid volume, lower incidence and number of nodules, and higher vascularity index (p < 0.05).
Conclusions
The patient's history of previous RT should be taken into consideration in the sonographic examination of the thyroid gland post‐RT. © 2014 Wiley Periodicals, Inc. J Clin Ultrasound 43:210–223, 2015</abstract><cop>United States</cop><pub>Blackwell Publishing Ltd</pub><pmid>25138465</pmid><doi>10.1002/jcu.22222</doi><tpages>14</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0091-2751 |
| ispartof | Journal of clinical ultrasound, 2015-05, Vol.43 (4), p.210-223 |
| issn | 0091-2751 1097-0096 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1826598939 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | hypothyroidism nasopharyngeal carcinoma radiotherapy thyroid Ultrasonic imaging ultrasonography |
| title | Sonographic appearance of thyroid glands in patients treated with intensity-modulated radiotherapy or conventional radiotherapy for nasopharyngeal carcinoma |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T22%3A43%3A56IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Sonographic%20appearance%20of%20thyroid%20glands%20in%20patients%20treated%20with%20intensity-modulated%20radiotherapy%20or%20conventional%20radiotherapy%20for%20nasopharyngeal%20carcinoma&rft.jtitle=Journal%20of%20clinical%20ultrasound&rft.au=Cheng,%20Sammy%20C.H.&rft.date=2015-05&rft.volume=43&rft.issue=4&rft.spage=210&rft.epage=223&rft.pages=210-223&rft.issn=0091-2751&rft.eissn=1097-0096&rft.coden=JCULDD&rft_id=info:doi/10.1002/jcu.22222&rft_dat=%3Cproquest_pubme%3E3649181581%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1671217074&rft_id=info:pmid/25138465&rfr_iscdi=true |