Tissue factor-targeted lidamycin inhibits growth and metastasis of colon carcinoma

Colon cancer is the third most common cancer in the world. The overexpression of tissue factor (TF) in colon cancer cells makes it an ideal target for colon cancer therapy. The purpose of the present study was to develop a TF-targeting energized fusion protein, mlFVII-LDP-AE, which is composed of a...

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Veröffentlicht in:	Oncology letters 2013-09, Vol.6 (3), p.801-806
Hauptverfasser:	ZHANG, QING, LIU, XIUJUN, LI, CAIHONG, LIAO, DONGSHENG, OUYANG, ZHIGANG, ZHENG, JUNNIAN, SONG, XU
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Breast cancer Cancer therapies Chemotherapy Chromatography colon carcinoma Colorectal cancer Cytotoxicity Deoxyribonucleic acid DNA Experiments factor VII Immunotherapy lidamycin Ligands Metastasis Oncology Proteins tissue factor Tumors
Online-Zugang:	Volltext
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