Effects of Maternal Exposure to a Reconstituted Mixture of Polychlorinated Biphenyls on Sex-Dependent Behaviors and Steroid Hormone Concentrations in Rats: Dose–Response Relationship

In a previous experiment, maternal exposure to a polychlorinated biphenyl (PCB) mixture reconstituted according to the congener pattern found in human breast milk resulted in decreased aromatase activity in the brain of newborn male rats, together with feminization of sweet preference behavior in ad...

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Veröffentlicht in:	Toxicology and applied pharmacology 2002-01, Vol.178 (2), p.71-81
Hauptverfasser:	Kaya, Hatice, Hany, Jürgen, Fastabend, Annemarie, Roth-Härer, Astrid, Winneke, Gerhard, Lilienthal, Hellmuth
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Behavior, Animal - drug effects Biological and medical sciences Body Weight - drug effects Brain - drug effects Brain - growth & development Chemical and industrial products toxicology. Toxic occupational diseases conditioned place preference Conditioning, Operant - drug effects development Dose-Response Relationship, Drug Environmental Pollutants - toxicity estradiol Estradiol - blood Female Food Preferences - drug effects Male Medical sciences Organ Size - drug effects polychlorinated biphenyls Polychlorinated Biphenyls - toxicity Pregnancy Prenatal Exposure Delayed Effects rat Rats Rats, Long-Evans Sex Characteristics Sex Differentiation - drug effects sexual dimorphism Steroids - metabolism sweet preference testosterone Testosterone - blood Testosterone - pharmacology Toxicology Various organic compounds
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