STIM2 Contributes to Enhanced Store-operated Ca Entry in Pulmonary Artery Smooth Muscle Cells from Patients with Idiopathic Pulmonary Arterial Hypertension

Pulmonary vasoconstriction and vascular remodeling are two major causes for elevated pulmonary vascular resistance and pulmonary arterial pressure in patients with idiopathic pulmonary arterial hypertension (IPAH). An increase in cytosolic free Ca(2+) concentration ([Ca(2+)](cyt)) in pulmonary arter...

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Veröffentlicht in:Pulmonary circulation 2011, Vol.1 (1), p.84-94
Hauptverfasser: Song, Michael Y, Makino, Ayako, Yuan, Jason X-J
Format: Artikel
Sprache:eng
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