Heparan Sulfate Modulates Kinin Release by Trypanosoma cruzi through the Activity of Cruzipain

Trypanosoma cruzi activates the kinin pathway through the activity of its major cysteine proteinase, cruzipain. Because kininogen molecules may be displayed on cell surfaces by binding to glycosaminoglycans, we examined whether the ability of cruzipain to release kinins from high molecular weight ki...

Ausführliche Beschreibung