Symptom Factor Analysis, Clinical Findings, and Functional Status in a Population-Based Case Control Study of Gulf War Unexplained Illness
Few epidemiological studies have been conducted that have incorporated clinical evaluations of Gulf War veterans with unexplained health symptoms and healthy controls. We conducted a mail survey of 2022 Gulf War veterans residing in the northwest United States and clinical examinations on a subset o...
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| Veröffentlicht in: | Journal of occupational and environmental medicine 2001-12, Vol.43 (12), p.1026-1040 |
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| container_title | Journal of occupational and environmental medicine |
| container_volume | 43 |
| creator | Bourdette, Dennis N. McCauley, Linda A. Barkhuizen, Andre Johnston, Wendy Wynn, Michael Joos, Sandra K. Storzbach, Daniel Shuell, Tomas Sticker, Diana |
| description | Few epidemiological studies have been conducted that have incorporated clinical evaluations of Gulf War veterans with unexplained health symptoms and healthy controls. We conducted a mail survey of 2022 Gulf War veterans residing in the northwest United States and clinical examinations on a subset of 443 responders who seemed to have unexplained health symptoms or were healthy. Few clinical differences were found between cases and controls. Th most frequent unexplained symptoms were cognitive/psychological, but significant overlap existed with musculoskeletal and fatigue symptoms. Over half of the veterans with unexplained musculoskeletal pain met the criteria for fibromyalgia, and a significant portion of the veterans with unexplained fatigue met the criteria for chronic fatigue syndrome. Similarities were found the clinical interpretation of unexplained illness in this population and statistical factor analysis performed by this study group and others. |
| doi_str_mv | 10.1097/00043764-200112000-00005 |
| format | Article |
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We conducted a mail survey of 2022 Gulf War veterans residing in the northwest United States and clinical examinations on a subset of 443 responders who seemed to have unexplained health symptoms or were healthy. Few clinical differences were found between cases and controls. Th most frequent unexplained symptoms were cognitive/psychological, but significant overlap existed with musculoskeletal and fatigue symptoms. Over half of the veterans with unexplained musculoskeletal pain met the criteria for fibromyalgia, and a significant portion of the veterans with unexplained fatigue met the criteria for chronic fatigue syndrome. Similarities were found the clinical interpretation of unexplained illness in this population and statistical factor analysis performed by this study group and others.</description><identifier>ISSN: 1076-2752</identifier><identifier>EISSN: 1536-5948</identifier><identifier>DOI: 10.1097/00043764-200112000-00005</identifier><identifier>PMID: 11765674</identifier><identifier>CODEN: JOEMFM</identifier><language>eng</language><publisher>Hagerstown, MD: Lippincott Williams & Wilkins</publisher><subject>Adult ; Biological and medical sciences ; Case-Control Studies ; Chronic illnesses ; cognitive ability ; fatigue ; Fatigue Syndrome, Chronic - etiology ; Fibromyalgia - etiology ; Gulf War ; Health Surveys ; Humans ; Male ; Medical sciences ; Middle East ; Miscellaneous ; musculoskeletal system ; Occupational Exposure - adverse effects ; Occupational Exposure - statistics & numerical data ; Occupational medicine ; Persian Gulf Syndrome - complications ; Persian Gulf Syndrome - epidemiology ; Persian Gulf Syndrome - etiology ; Persian Gulf War ; Public health. Hygiene-occupational medicine ; Questionnaires ; Surveys and Questionnaires ; United States - epidemiology ; Veterans ; Veterans - statistics & numerical data ; Warfare</subject><ispartof>Journal of occupational and environmental medicine, 2001-12, Vol.43 (12), p.1026-1040</ispartof><rights>Copyright © 2001 American College of Occupational and Environmental Medicine</rights><rights>2002 INIST-CNRS</rights><rights>Copyright Lippincott Williams & Wilkins Dec 2001</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/44995831$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/44995831$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>314,776,780,799,27901,27902,57992,58225</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=14101641$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11765674$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bourdette, Dennis N.</creatorcontrib><creatorcontrib>McCauley, Linda A.</creatorcontrib><creatorcontrib>Barkhuizen, Andre</creatorcontrib><creatorcontrib>Johnston, Wendy</creatorcontrib><creatorcontrib>Wynn, Michael</creatorcontrib><creatorcontrib>Joos, Sandra K.</creatorcontrib><creatorcontrib>Storzbach, Daniel</creatorcontrib><creatorcontrib>Shuell, Tomas</creatorcontrib><creatorcontrib>Sticker, Diana</creatorcontrib><title>Symptom Factor Analysis, Clinical Findings, and Functional Status in a Population-Based Case Control Study of Gulf War Unexplained Illness</title><title>Journal of occupational and environmental medicine</title><addtitle>J Occup Environ Med</addtitle><description>Few epidemiological studies have been conducted that have incorporated clinical evaluations of Gulf War veterans with unexplained health symptoms and healthy controls. We conducted a mail survey of 2022 Gulf War veterans residing in the northwest United States and clinical examinations on a subset of 443 responders who seemed to have unexplained health symptoms or were healthy. Few clinical differences were found between cases and controls. Th most frequent unexplained symptoms were cognitive/psychological, but significant overlap existed with musculoskeletal and fatigue symptoms. Over half of the veterans with unexplained musculoskeletal pain met the criteria for fibromyalgia, and a significant portion of the veterans with unexplained fatigue met the criteria for chronic fatigue syndrome. Similarities were found the clinical interpretation of unexplained illness in this population and statistical factor analysis performed by this study group and others.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Case-Control Studies</subject><subject>Chronic illnesses</subject><subject>cognitive ability</subject><subject>fatigue</subject><subject>Fatigue Syndrome, Chronic - etiology</subject><subject>Fibromyalgia - etiology</subject><subject>Gulf War</subject><subject>Health Surveys</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle East</subject><subject>Miscellaneous</subject><subject>musculoskeletal system</subject><subject>Occupational Exposure - adverse effects</subject><subject>Occupational Exposure - statistics & numerical data</subject><subject>Occupational medicine</subject><subject>Persian Gulf Syndrome - complications</subject><subject>Persian Gulf Syndrome - epidemiology</subject><subject>Persian Gulf Syndrome - etiology</subject><subject>Persian Gulf War</subject><subject>Public health. Hygiene-occupational medicine</subject><subject>Questionnaires</subject><subject>Surveys and Questionnaires</subject><subject>United States - epidemiology</subject><subject>Veterans</subject><subject>Veterans - statistics & numerical data</subject><subject>Warfare</subject><issn>1076-2752</issn><issn>1536-5948</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2001</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpd0VtrFTEQAOBFFHvRn6AEwT65mvvlsS6eWigo1OLjMm4SySGbrJsNeP6Cv9qUHhV8mJmQ-RjIpOsQwW8JNuodxpgzJXlPMSakJdy3wOJRd0oEk70wXD9uZ6xkT5WgJ91ZKftmBcHiaXdCiJJCKn7a_bo9zMuWZ7SDacsrukwQDyWUN2iIIYUJItqFZEP63q4gWbSradpCbgzdbrDVgkJCgD7npUa4b_TvoTiLhpbRkNO25ntZ7QFlj65q9OgrrOguuZ9LhJAavY4xuVKedU88xOKeH-t5d7f78GX42N98uroeLm_6PSNq6423VHNJtcUMW2-c8UZ7DNQJKgAz662anLBaWca8ooYxsE5TKUByrCd23l08zF3W_KO6so1zKJOLEZLLtYxEUyEx1Q2--g_uc13by8tICZVaE2MaenlE9dvs7LisYYb1MP5ZcQOvjwBKW6dfIU2h_HOcYCI5ae7Fg9uX9hF_-5wbIzQj7DdnApXY</recordid><startdate>20011201</startdate><enddate>20011201</enddate><creator>Bourdette, Dennis N.</creator><creator>McCauley, Linda A.</creator><creator>Barkhuizen, Andre</creator><creator>Johnston, Wendy</creator><creator>Wynn, Michael</creator><creator>Joos, Sandra K.</creator><creator>Storzbach, Daniel</creator><creator>Shuell, Tomas</creator><creator>Sticker, Diana</creator><general>Lippincott Williams & Wilkins</general><general>Lippincott Williams & Wilkins Ovid Technologies</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7T2</scope><scope>7U7</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>K9.</scope><scope>7U2</scope></search><sort><creationdate>20011201</creationdate><title>Symptom Factor Analysis, Clinical Findings, and Functional Status in a Population-Based Case Control Study of Gulf War Unexplained Illness</title><author>Bourdette, Dennis N. ; McCauley, Linda A. ; Barkhuizen, Andre ; Johnston, Wendy ; Wynn, Michael ; Joos, Sandra K. ; Storzbach, Daniel ; Shuell, Tomas ; Sticker, Diana</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j317t-9fd284628d030df9e9f98f0a2e525a03dfd7ce5d87d33f72933ade8265a6408c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2001</creationdate><topic>Adult</topic><topic>Biological and medical sciences</topic><topic>Case-Control Studies</topic><topic>Chronic illnesses</topic><topic>cognitive ability</topic><topic>fatigue</topic><topic>Fatigue Syndrome, Chronic - etiology</topic><topic>Fibromyalgia - etiology</topic><topic>Gulf War</topic><topic>Health Surveys</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle East</topic><topic>Miscellaneous</topic><topic>musculoskeletal system</topic><topic>Occupational Exposure - adverse effects</topic><topic>Occupational Exposure - statistics & numerical data</topic><topic>Occupational medicine</topic><topic>Persian Gulf Syndrome - complications</topic><topic>Persian Gulf Syndrome - epidemiology</topic><topic>Persian Gulf Syndrome - etiology</topic><topic>Persian Gulf War</topic><topic>Public health. 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| ispartof | Journal of occupational and environmental medicine, 2001-12, Vol.43 (12), p.1026-1040 |
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| subjects | Adult Biological and medical sciences Case-Control Studies Chronic illnesses cognitive ability fatigue Fatigue Syndrome, Chronic - etiology Fibromyalgia - etiology Gulf War Health Surveys Humans Male Medical sciences Middle East Miscellaneous musculoskeletal system Occupational Exposure - adverse effects Occupational Exposure - statistics & numerical data Occupational medicine Persian Gulf Syndrome - complications Persian Gulf Syndrome - epidemiology Persian Gulf Syndrome - etiology Persian Gulf War Public health. Hygiene-occupational medicine Questionnaires Surveys and Questionnaires United States - epidemiology Veterans Veterans - statistics & numerical data Warfare |
| title | Symptom Factor Analysis, Clinical Findings, and Functional Status in a Population-Based Case Control Study of Gulf War Unexplained Illness |
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