In vitro and in vivo assessment of novel pH-sensitive interpenetrating polymer networks of a graft copolymer for gastro-protective delivery of ketoprofen

The pH-sensitive polyacrylamide-grafted-tamarind seed polysaccharide (PAam- g -TSP) copolymer was synthesized under microwave irradiation in the presence of ceric ammonium nitrate in order to initiate the reaction. The reaction mixture was subjected to hydrolysis in alkaline medium. The copolymer wa...

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Veröffentlicht in:RSC advances 2016-01, Vol.6 (69), p.64344-64356
Hauptverfasser: Boppana, Rashmi, Kulkarni, Raghavendra V., Mohan, G. Krishna, Mutalik, Srinivas, Aminabhavi, Tejraj M.
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Sprache:eng
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