Crossing the blood–brain–barrier with transferrin conjugated carbon dots: A zebrafish model study

[Display omitted] •Human transferrin was covalently conjugated to C-Dots.•Transferrin-C-Dots could enter the CNS by crossing the BBB while C-Dots could not.•Zebrafish was used as an in vivo model for the BBB crossing study. Drug delivery to the central nervous system (CNS) in biological systems rema...

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Veröffentlicht in:Colloids and surfaces, B, Biointerfaces B, Biointerfaces, 2016-09, Vol.145, p.251-256
Hauptverfasser: Li, Shanghao, Peng, Zhili, Dallman, Julia, Baker, James, Othman, Abdelhameed M., Blackwelder, Patrica L., Leblanc, Roger M.
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Sprache:eng
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