A new convenient synthetic approach to diarylpyrimidines

A new synthetic method in pyrimidine chemistry has been developed. 2,2,2-Trichloroethylideneacetophenones, easily available from chloral and acetophenones, reacted with benzamidines to provide novel 2,6-diaryl-6-hydroxy-4-trichloromethyl-1,4,5,6-tetrahydropyrimidines in near quantitative yields. Eff...

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Veröffentlicht in:	Tetrahedron 2016-07, Vol.72 (27-28), p.3922-3929
Hauptverfasser:	Guirado, Antonio, Alarcón, Enrique, Vicente, Yesica, Andreu, Raquel, Bautista, Delia, Gálvez, Jesús
Format:	Artikel
Sprache:	eng
Schlagworte:	Accessibility Acetophenones Benzamidines Chloral Chloroform Diffraction Molecular structure Pyrimidines Tetrahedrons Trichloroethylideneacetophenones X-rays
Online-Zugang:	Volltext
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