Enhancing Tumor Cell Response to Chemotherapy through the Targeted Delivery of Platinum Drugs Mediated by Highly Stable, Multifunctional Carboxymethylcellulose-Coated Magnetic Nanoparticles

The fabrication of nanoparticles using different formulations, and which can be used for the delivery of chemotherapeutics, has recently attracted considerable attention. We describe herein an innovative approach that may ultimately allow for the selective delivery of anticancer drugs to tumor cells...

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Veröffentlicht in:	Chemistry : a European journal 2016-07, Vol.22 (28), p.9750-9759
Hauptverfasser:	Medříková, Zdenka, Novohradsky, Vojtech, Zajac, Juraj, Vrána, Oldřich, Kasparkova, Jana, Bakandritsos, Aristides, Petr, Martin, Zbořil, Radek, Brabec, Viktor
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - administration & dosage Antineoplastic Agents - chemistry Antineoplastic Agents - pharmacokinetics Antineoplastic Agents - pharmacology Biocompatibility Carboxymethylcellulose Sodium - chemistry Carboxymethylcellulose Sodium - pharmacokinetics Cell Line, Tumor Chemistry Chemotherapy Cisplatin - administration & dosage Cisplatin - chemistry Cisplatin - pharmacokinetics Cisplatin - pharmacology cytotoxicity drug delivery Drug Delivery Systems Drugs Folic Acid - chemistry Humans Localization magnetic properties Magnetite Nanoparticles - chemistry Nanoparticles Platinum Platinum - chemistry Position (location) Tumors
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