Two-wheel drive-based DNA nanomachine and its sensing potential for highly sensitive analysis of cancer-related gene

Abstract With the biological significance and important advances of nano-scale DNA devices, scientific activities have been directed toward developing molecular machinery. In this work, we present a novel two-wheel drive-based DNA nanomachine composed of one signaling recognition probe (SRP), one la...

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Veröffentlicht in:	Biomaterials 2016-09, Vol.100, p.110-117
Hauptverfasser:	Xu, Jianguo, Wu, Zai-Sheng, Wang, Zhenmeng, Li, Hongling, Le, Jingqing, Jia, Lee
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Advanced Basic Science Base Sequence Biosensing Techniques - methods Cancer-related gene Dentistry Deoxyribonucleic acid Devices DNA - chemistry DNA - genetics DNA nanomachine DNA Primers - chemistry DNA Primers - genetics Fluorescence Humans Limit of Detection Nanostructure Nanotechnology Neoplasms - genetics Nucleic Acid Hybridization Point Mutation Polymerization Recognition Signal amplification Strands Tumor Suppressor Protein p53 - genetics Two-wheel drive Wheels
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