Spatial location of indomethacin associated with unimeric amphiphilic carrier macromolecules as determined by nuclear magnetic resonance spectroscopy

A combination of nuclear magnetic resonance (NMR) techniques including, proton NMR, relaxation analysis, two‐dimensional nuclear Overhauser effect spectroscopy, and diffusion‐ordered spectroscopy, has been used to demonstrate the spatial location of indomethacin within a unimolecular micelle. Unders...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Magnetic resonance in chemistry 2016-07, Vol.54 (7), p.575-583
Hauptverfasser:	Orban, David E., Moretti, Alysha, Uhrich, Kathryn E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Carriers Design engineering Drug Carriers - chemistry drug loading Drugs Encapsulation indomethacin Indomethacin - chemistry Isomerism Macromolecular Substances - chemistry macromolecule Macromolecules Magnetic Resonance Spectroscopy micelle Micelles Molecular Structure NMR Nuclear magnetic resonance Solvents - chemistry Spectroscopy Structure-Activity Relationship Surface-Active Agents - chemistry surfactant unimolecular Water - chemistry
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!