A toolkit for bioimaging using near-infrared AgInS sub(2)/ZnS quantum dots
Presented are a set of procedures to produce water-soluble AgInS sub(2)/ZnS near-infrared emitting quantum dots for use as biological imaging agents. The known difficulty of producing near-infrared core/shell materials is resolved by overcoating the AgInS sub(2) cores at a low temperature using high...
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Veröffentlicht in: | Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2015-10, Vol.3 (41), p.8188-8196 |
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container_title | Journal of materials chemistry. B, Materials for biology and medicine |
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creator | Shamirian, Armen Appelbe, Oliver Zhang, Qingbei Ganesh, Balaji Kron, Stephen J Snee, Preston T |
description | Presented are a set of procedures to produce water-soluble AgInS sub(2)/ZnS near-infrared emitting quantum dots for use as biological imaging agents. The known difficulty of producing near-infrared core/shell materials is resolved by overcoating the AgInS sub(2) cores at a low temperature using highly reactive precursors. Several methods are explored to impart water solubility of the hydrophobic as-prepared materials. Insofar as achieving aqueous dispersion of quantum dots has only limited biological utility, several methods to further functionalize them are examined. In vivo studies are conducted using these quantum dots to demonstrate the ability to model delivery of nanoparticles to the tumour microenvironment. |
doi_str_mv | 10.1039/c5tb00247h |
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source | Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
subjects | Biology Nanoparticles Precursors Quantum dots Solubility Utilities Zinc sulfides |
title | A toolkit for bioimaging using near-infrared AgInS sub(2)/ZnS quantum dots |
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