A toolkit for bioimaging using near-infrared AgInS sub(2)/ZnS quantum dots

Presented are a set of procedures to produce water-soluble AgInS sub(2)/ZnS near-infrared emitting quantum dots for use as biological imaging agents. The known difficulty of producing near-infrared core/shell materials is resolved by overcoating the AgInS sub(2) cores at a low temperature using high...

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Veröffentlicht in:Journal of materials chemistry. B, Materials for biology and medicine Materials for biology and medicine, 2015-10, Vol.3 (41), p.8188-8196
Hauptverfasser: Shamirian, Armen, Appelbe, Oliver, Zhang, Qingbei, Ganesh, Balaji, Kron, Stephen J, Snee, Preston T
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container_issue 41
container_start_page 8188
container_title Journal of materials chemistry. B, Materials for biology and medicine
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creator Shamirian, Armen
Appelbe, Oliver
Zhang, Qingbei
Ganesh, Balaji
Kron, Stephen J
Snee, Preston T
description Presented are a set of procedures to produce water-soluble AgInS sub(2)/ZnS near-infrared emitting quantum dots for use as biological imaging agents. The known difficulty of producing near-infrared core/shell materials is resolved by overcoating the AgInS sub(2) cores at a low temperature using highly reactive precursors. Several methods are explored to impart water solubility of the hydrophobic as-prepared materials. Insofar as achieving aqueous dispersion of quantum dots has only limited biological utility, several methods to further functionalize them are examined. In vivo studies are conducted using these quantum dots to demonstrate the ability to model delivery of nanoparticles to the tumour microenvironment.
doi_str_mv 10.1039/c5tb00247h
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source Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection
subjects Biology
Nanoparticles
Precursors
Quantum dots
Solubility
Utilities
Zinc sulfides
title A toolkit for bioimaging using near-infrared AgInS sub(2)/ZnS quantum dots
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