Medulloblastoma with epithelioid features in the cerebellar vermis

Medulloblastoma with epithelioid features in the cerebellar vermis

A 6-year-old girl was admitted with a mass lesion in the cerebellar vermis. She underwent subtotal tumor resection, and on immunohistopathology the tumor consisted of two different parts: typical medulloblastoma (MB) characteristics and atypical teratoid/rhabdoid tumor (AT/RT) features, despite posi...

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Veröffentlicht in:Pediatrics international : official journal of the Japan Pediatric Society 2016, Vol.58 (9), p.908-912
Hauptverfasser: Miyata, Kenji, Hori, Toshinori, Yamakawa, Kiyoshi, Takasu, Michihiko, Hayakawa, Tomohito, Shimomura, Yasuto, Iwata, Atsuko, Okumura, Akihisa, Nakura, Takahiro, Jyoko, Masahiro, Mori, Yoshimasa, Takahashi, Emiko, Hirato, Junko
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container_issue 9
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container_title Pediatrics international : official journal of the Japan Pediatric Society
container_volume 58
creator Miyata, Kenji
Hori, Toshinori
Yamakawa, Kiyoshi
Takasu, Michihiko
Hayakawa, Tomohito
Shimomura, Yasuto
Iwata, Atsuko
Okumura, Akihisa
Nakura, Takahiro
Jyoko, Masahiro
Mori, Yoshimasa
Takahashi, Emiko
Hirato, Junko
description A 6-year-old girl was admitted with a mass lesion in the cerebellar vermis. She underwent subtotal tumor resection, and on immunohistopathology the tumor consisted of two different parts: typical medulloblastoma (MB) characteristics and atypical teratoid/rhabdoid tumor (AT/RT) features, despite positive integrase interactor 1 expression. The patient was diagnosed with MB with epithelioid features. Chemoradiation therapy was started because of tumor recurrence at the primary site and dissemination to the spinal cord, as determined on magnetic resonance imaging 2 weeks after surgery. The patient died due to tumor progression 13 months after initial diagnosis, although transient partial remission was achieved.
doi_str_mv 10.1111/ped.12998
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title Medulloblastoma with epithelioid features in the cerebellar vermis
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