Mushroom body signaling is required for locomotor activity rhythms in Drosophila

•The importance of MBs in behavioral rhythmicity remains controversial in Drosophila.•The locomotor activity in MB-ablated flies is substantially rhythmic.•Activation of MB neurons induces arrhythmic locomotor activity.•We found that blocking of neurotransmission in MBs induces behavioral arrhythmic...

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Veröffentlicht in:	Neuroscience research 2016-10, Vol.111, p.25-33
Hauptverfasser:	Mabuchi, Ikumi, Shimada, Naoto, Sato, Shoma, Ienaga, Kahori, Inami, Show, Sakai, Takaomi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Circadian Rhythm Circadian rhythms Darkness Drosophila Drosophila melanogaster - genetics Drosophila melanogaster - physiology Drosophila Proteins - genetics Dynamins - genetics GAL80/GAL4/UAS Locomotion Locomotor activity Mushroom bodies Mushroom Bodies - physiology Mutation Neurons - physiology shibirets1 Signal Transduction Synaptic Transmission
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