Binding of synthetic LKEKK peptide to human T-lymphocytes

The synthetic peptide LKEKK corresponding to sequence 16-20 of human thymosin-α 1 and 131-135 of human interferon-α 2 was labeled with tritium to specific activity 28 Ci/mol. The [ 3 H]LKEKK bound with high affinity ( K d = 3.7 ± 0.3 nM) to donor blood T-lymphocytes. Treatment of cells with trypsin...

Ausführliche Beschreibung