HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression

At present, HOXC13 is the only member of the HOX multigene family that produces a fragile hair phenotype when mutated or overexpressed in mice. To determine whether hair keratin genes are targets for this transcription factor, we analyzed the HOXC13 responsiveness of human hair keratin genes, whose...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of biological chemistry 2002-02, Vol.277 (5), p.3718-3726
Hauptverfasser:	Jave-Suarez, Luis Felipe, Winter, Hermelita, Langbein, Lutz, Rogers, Michael A., Schweizer, Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Binding Sites Cell Line Dipodomys DNA Primers Fluorescent Antibody Technique, Indirect Gene Expression Regulation Genes, Reporter Hair Follicle - physiology Homeodomain Proteins - genetics Homeodomain Proteins - metabolism HOXC13 gene Keratins - genetics Mice Molecular Sequence Data Promoter Regions, Genetic Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Sequence Alignment Sequence Deletion Sequence Homology, Nucleic Acid TATA Box Transcription, Genetic Transfection trichocytes
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!