Preoperative Bowel Preparation before Elective Bowel Resection or Ostomy Closure in the Pediatric Patient Population Has No Impact on Outcomes: A Prospective Randomized Study
The role of preoperative bowel prep in the pediatric surgical population is uncertain. We performed a randomized prospective study to evaluate noninferiority between the presence or absence of a preoperative bowel prep in elective pediatric bowel surgery on postoperative outcomes. Patients aged thre...
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Veröffentlicht in: | The American surgeon 2016-09, Vol.82 (9), p.801-806 |
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description | The role of preoperative bowel prep in the pediatric surgical population is uncertain. We performed a randomized prospective study to evaluate noninferiority between the presence or absence of a preoperative bowel prep in elective pediatric bowel surgery on postoperative outcomes. Patients aged three months to 18 years were recruited and randomized to the bowel prep group or the no bowel prep group. Patients were evaluated in-hospital and at postoperative clinic visits. Thirty-two patients were recruited; 18 in the bowel prep group and 14 in the no bowel prep group. There was no statistical difference (P > 0.05) in complications between the groups. Complications were observed in five patients in each group (27.8% and 35.7%, respectively). In the bowel prep group, two (11.1%) had wound infection (vs three, 21.4%), 0 had an intra-abdominal abscess (vs one, 7.1%), one (5.6%) had sepsis (vs one, 7.1%), one (5.6%) had an anastomotic leak (vs 0), and three (16.7%) had a bowel obstruction (vs one, 7.1%). There were no extra-abdominal complications. There were no significant differences in complications between the two groups. Further research is warranted, but may require a multi-institutional trial to recruit sufficient numbers to make conclusions about the significance of the need for bowel prep. |
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We performed a randomized prospective study to evaluate noninferiority between the presence or absence of a preoperative bowel prep in elective pediatric bowel surgery on postoperative outcomes. Patients aged three months to 18 years were recruited and randomized to the bowel prep group or the no bowel prep group. Patients were evaluated in-hospital and at postoperative clinic visits. Thirty-two patients were recruited; 18 in the bowel prep group and 14 in the no bowel prep group. There was no statistical difference (P > 0.05) in complications between the groups. Complications were observed in five patients in each group (27.8% and 35.7%, respectively). In the bowel prep group, two (11.1%) had wound infection (vs three, 21.4%), 0 had an intra-abdominal abscess (vs one, 7.1%), one (5.6%) had sepsis (vs one, 7.1%), one (5.6%) had an anastomotic leak (vs 0), and three (16.7%) had a bowel obstruction (vs one, 7.1%). There were no extra-abdominal complications. There were no significant differences in complications between the two groups. Further research is warranted, but may require a multi-institutional trial to recruit sufficient numbers to make conclusions about the significance of the need for bowel prep.</description><identifier>ISSN: 0003-1348</identifier><identifier>EISSN: 1555-9823</identifier><identifier>DOI: 10.1177/000313481608200941</identifier><identifier>PMID: 27670567</identifier><language>eng</language><publisher>Los Angeles, CA: SAGE Publications</publisher><subject>Abdomen ; Adolescent ; Antibiotics ; Cathartics - administration & dosage ; Child ; Child, Preschool ; Colon ; Colonoscopy ; Digestive System Surgical Procedures ; Elective Surgical Procedures ; Electrolytes - administration & dosage ; Female ; Follow-Up Studies ; Hospitals ; Humans ; Infant ; Infections ; Intestines - surgery ; Male ; Mortality ; Ostomy ; Patients ; Pediatrics ; Polyethylene Glycols - administration & dosage ; Postoperative Complications - etiology ; Postoperative Complications - prevention & control ; Preoperative Care - methods ; Prospective Studies ; Surgery ; Treatment Outcome</subject><ispartof>The American surgeon, 2016-09, Vol.82 (9), p.801-806</ispartof><rights>2016 Southeastern Surgical Congress</rights><rights>Copyright Southeastern Surgical Congress Sep 2016</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c415t-13f670560b51a0ff1ec0f3c2420e7d3b0ff340bb887c68120ed9b99f0c9f02993</citedby><cites>FETCH-LOGICAL-c415t-13f670560b51a0ff1ec0f3c2420e7d3b0ff340bb887c68120ed9b99f0c9f02993</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/000313481608200941$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/000313481608200941$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21799,27903,27904,43600,43601</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27670567$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shah, Mansi</creatorcontrib><creatorcontrib>Ellis, Clayton T.</creatorcontrib><creatorcontrib>Phillips, Michael R.</creatorcontrib><creatorcontrib>Marzinsky, Amy</creatorcontrib><creatorcontrib>Adamson, William</creatorcontrib><creatorcontrib>Weiner, Timothy</creatorcontrib><creatorcontrib>Erickson, Kimberly</creatorcontrib><creatorcontrib>Lee, Sang</creatorcontrib><creatorcontrib>Lange, Patricia A.</creatorcontrib><creatorcontrib>McLean, Sean E.</creatorcontrib><title>Preoperative Bowel Preparation before Elective Bowel Resection or Ostomy Closure in the Pediatric Patient Population Has No Impact on Outcomes: A Prospective Randomized Study</title><title>The American surgeon</title><addtitle>Am Surg</addtitle><description>The role of preoperative bowel prep in the pediatric surgical population is uncertain. We performed a randomized prospective study to evaluate noninferiority between the presence or absence of a preoperative bowel prep in elective pediatric bowel surgery on postoperative outcomes. Patients aged three months to 18 years were recruited and randomized to the bowel prep group or the no bowel prep group. Patients were evaluated in-hospital and at postoperative clinic visits. Thirty-two patients were recruited; 18 in the bowel prep group and 14 in the no bowel prep group. There was no statistical difference (P > 0.05) in complications between the groups. Complications were observed in five patients in each group (27.8% and 35.7%, respectively). In the bowel prep group, two (11.1%) had wound infection (vs three, 21.4%), 0 had an intra-abdominal abscess (vs one, 7.1%), one (5.6%) had sepsis (vs one, 7.1%), one (5.6%) had an anastomotic leak (vs 0), and three (16.7%) had a bowel obstruction (vs one, 7.1%). There were no extra-abdominal complications. There were no significant differences in complications between the two groups. Further research is warranted, but may require a multi-institutional trial to recruit sufficient numbers to make conclusions about the significance of the need for bowel prep.</description><subject>Abdomen</subject><subject>Adolescent</subject><subject>Antibiotics</subject><subject>Cathartics - administration & dosage</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Colon</subject><subject>Colonoscopy</subject><subject>Digestive System Surgical Procedures</subject><subject>Elective Surgical Procedures</subject><subject>Electrolytes - administration & dosage</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>Hospitals</subject><subject>Humans</subject><subject>Infant</subject><subject>Infections</subject><subject>Intestines - surgery</subject><subject>Male</subject><subject>Mortality</subject><subject>Ostomy</subject><subject>Patients</subject><subject>Pediatrics</subject><subject>Polyethylene Glycols - administration & dosage</subject><subject>Postoperative Complications - 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administration & dosage</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Colon</topic><topic>Colonoscopy</topic><topic>Digestive System Surgical Procedures</topic><topic>Elective Surgical Procedures</topic><topic>Electrolytes - administration & dosage</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>Hospitals</topic><topic>Humans</topic><topic>Infant</topic><topic>Infections</topic><topic>Intestines - surgery</topic><topic>Male</topic><topic>Mortality</topic><topic>Ostomy</topic><topic>Patients</topic><topic>Pediatrics</topic><topic>Polyethylene Glycols - administration & dosage</topic><topic>Postoperative Complications - etiology</topic><topic>Postoperative Complications - prevention & control</topic><topic>Preoperative Care - methods</topic><topic>Prospective Studies</topic><topic>Surgery</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shah, Mansi</creatorcontrib><creatorcontrib>Ellis, Clayton T.</creatorcontrib><creatorcontrib>Phillips, Michael R.</creatorcontrib><creatorcontrib>Marzinsky, Amy</creatorcontrib><creatorcontrib>Adamson, William</creatorcontrib><creatorcontrib>Weiner, Timothy</creatorcontrib><creatorcontrib>Erickson, Kimberly</creatorcontrib><creatorcontrib>Lee, Sang</creatorcontrib><creatorcontrib>Lange, Patricia A.</creatorcontrib><creatorcontrib>McLean, Sean E.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Docstoc</collection><collection>University Readers</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Proquest Nursing & Allied Health Source</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>SIRS Editorial</collection><collection>MEDLINE - Academic</collection><jtitle>The American surgeon</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shah, Mansi</au><au>Ellis, Clayton T.</au><au>Phillips, Michael R.</au><au>Marzinsky, Amy</au><au>Adamson, William</au><au>Weiner, Timothy</au><au>Erickson, Kimberly</au><au>Lee, Sang</au><au>Lange, Patricia A.</au><au>McLean, Sean E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Preoperative Bowel Preparation before Elective Bowel Resection or Ostomy Closure in the Pediatric Patient Population Has No Impact on Outcomes: A Prospective Randomized Study</atitle><jtitle>The American surgeon</jtitle><addtitle>Am Surg</addtitle><date>2016-09</date><risdate>2016</risdate><volume>82</volume><issue>9</issue><spage>801</spage><epage>806</epage><pages>801-806</pages><issn>0003-1348</issn><eissn>1555-9823</eissn><abstract>The role of preoperative bowel prep in the pediatric surgical population is uncertain. We performed a randomized prospective study to evaluate noninferiority between the presence or absence of a preoperative bowel prep in elective pediatric bowel surgery on postoperative outcomes. Patients aged three months to 18 years were recruited and randomized to the bowel prep group or the no bowel prep group. Patients were evaluated in-hospital and at postoperative clinic visits. Thirty-two patients were recruited; 18 in the bowel prep group and 14 in the no bowel prep group. There was no statistical difference (P > 0.05) in complications between the groups. Complications were observed in five patients in each group (27.8% and 35.7%, respectively). In the bowel prep group, two (11.1%) had wound infection (vs three, 21.4%), 0 had an intra-abdominal abscess (vs one, 7.1%), one (5.6%) had sepsis (vs one, 7.1%), one (5.6%) had an anastomotic leak (vs 0), and three (16.7%) had a bowel obstruction (vs one, 7.1%). There were no extra-abdominal complications. There were no significant differences in complications between the two groups. Further research is warranted, but may require a multi-institutional trial to recruit sufficient numbers to make conclusions about the significance of the need for bowel prep.</abstract><cop>Los Angeles, CA</cop><pub>SAGE Publications</pub><pmid>27670567</pmid><doi>10.1177/000313481608200941</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Abdomen Adolescent Antibiotics Cathartics - administration & dosage Child Child, Preschool Colon Colonoscopy Digestive System Surgical Procedures Elective Surgical Procedures Electrolytes - administration & dosage Female Follow-Up Studies Hospitals Humans Infant Infections Intestines - surgery Male Mortality Ostomy Patients Pediatrics Polyethylene Glycols - administration & dosage Postoperative Complications - etiology Postoperative Complications - prevention & control Preoperative Care - methods Prospective Studies Surgery Treatment Outcome |
title | Preoperative Bowel Preparation before Elective Bowel Resection or Ostomy Closure in the Pediatric Patient Population Has No Impact on Outcomes: A Prospective Randomized Study |
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