Proteolytic modulation of factor Xaaantithrombin complex enhances fibrinolysis in plasma

Our previous work showed that purified coagulation factor Xa (FXa) acquires fibrinolysis cofactor activity after plasmin-mediated cleavage. The predominant functional species is a non-covalent heterodimer of 33 and 13 kDa, termed Xa33/13, which has predicted newly exposed C-terminal lysines that are...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochimica et biophysica acta. Proteins and proteomics 2013-06, Vol.1834 (6), p.989-995
Hauptverfasser:	Talbot, Kimberley, Meixner, Scott C, Pryzdial, Edward LG
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!