Flavonoids from tartary buckwheat induce G2/M cell cycle arrest and apoptosis in human hepatoma HepG2 cells

The cytotoxicity and antioxidant activity on human hepa toma cell line HepG2 of three flavonoids homogenous com pounds from tartary buckwheat seeds and bran, namely quercetin, isoquercetin, and rutin, were investigated. The total antioxidant competency detection results indicated that the antioxidan...

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Veröffentlicht in:	Acta biochimica et biophysica Sinica 2014-06, Vol.46 (6), p.460-470
Hauptverfasser:	Li, Yuying, Duan, Shizhao, Jia, Haiyan, Bai, Chongzhi, Zhang, Liwei, Wang, Zhuanhua
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - metabolism Apoptosis - drug effects Base Sequence Carcinoma, Hepatocellular - pathology Cell Division - drug effects Cell Line, Tumor DNA Primers Flavonoids - pharmacology Flow Cytometry G2 Phase - drug effects HepG2细胞 Humans Reactive Oxygen Species - metabolism Reverse Transcriptase Polymerase Chain Reaction 总抗氧化能力植物类黄酮细胞凋亡细胞周期阻滞细胞株苦荞
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