Somatic Copy Number Abnormalities and Mutations in PI3K/AKT/mTOR Pathway Have Prognostic Significance for Overall Survival in Platinum Treated Locally Advanced or Metastatic Urothelial Tumors: e0124711

Background An integrative analysis was conducted to identify genomic alterations at a pathway level that could predict overall survival (OS) in patients with advanced urothelial carcinoma (UC) treated with platinum-based chemotherapy. Patients and Methods DNA and RNA were extracted from 103 formalin...

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Veröffentlicht in:	PloS one 2015-06, Vol.10 (6)
Hauptverfasser:	Bellmunt, Joaquim, Werner, Lillian, Leow, Jeffrey J, Mullane, Stephanie A, Fay, Andre P, Riester, Markus, Hummelen, Paul Van, Taplin, Mary-Ellen, Choueiri, Toni K, Allen, Eliezer Van
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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