An important role of the hepcidin-ferroportin signaling in affecting tumor growth and metastasis

Epidemiological and experimental studies have suggested that deregulated hepcidin-ferroportin （FPN） signaling is associated with the increased risk of cancers. However, the effects of deregulated hepcidin-FPN signaling on tumor behaviors such as metastasis and epithelial to mesenchymal tran- sition...

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Veröffentlicht in:	Acta biochimica et biophysica Sinica 2015-09, Vol.47 (9), p.703-715
Hauptverfasser:	Guo, Wenli, Zhang, Shuping, Chen, Yue, Zhang, Daoqiang, Yuan, Lin, Cong, Haibo, Liu, Sijin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Breast Neoplasms - metabolism Breast Neoplasms - pathology Cation Transport Proteins - metabolism Cell Line, Tumor Cell Proliferation Female FPN hepcidin Hepcidins - genetics Hepcidins - metabolism Humans Mice Neoplasm Metastasis Signal Transduction 信号通路生长肺癌细胞肿瘤膜铁转运蛋白
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