Astrogliosis in the Adult and Developing CNS: Is There a Role for Proinflammatory Cytokines?

Astrogliosis, characterized by the enhanced expression of GFAP, represents a remarkably homotypic response of astrocytes to all types of injuries of the CNS, including injuries of the developing CNS. As such, astrocytes serve as microsensors of the “injured” microenvironment regardless of their loca...

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Veröffentlicht in:	Neurotoxicology (Park Forest South) 2001-10, Vol.22 (5), p.607-618
Hauptverfasser:	Little, A.R, O’Callaghan, J.P
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Astrocytes - metabolism Astrocytes - pathology Astrogliosis Central Nervous System - growth & development Central Nervous System - metabolism Central Nervous System - pathology Chemokines CNS Cytokines Cytokines - antagonists & inhibitors Cytokines - biosynthesis Cytokines - physiology GFAP Gliosis Gliosis - etiology Gliosis - metabolism Gliosis - pathology Gliosis - prevention & control Humans Inflammation Inflammation - etiology Inflammation - pathology
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