$Pretransplantation Anti-CCR4 Antibody Mogamulizumab Against Adult T-Cell Leukemia/Lymphoma Is Associated With Significantly Increased Risks of Severe and Corticosteroid-Refractory Graft-Versus-Host Disease, Nonrelapse Mortality, and Overall Mortality$

Pretransplantation Anti-CCR4 Antibody Mogamulizumab Against Adult T-Cell Leukemia/Lymphoma Is Associated With Significantly Increased Risks of Severe and Corticosteroid-Refractory Graft-Versus-Host Disease, Nonrelapse Mortality, and Overall Mortality

Allogeneic hematopoietic stem-cell transplantation (allo-HSCT) is one important treatment option for patients with aggressive adult T-cell leukemia/lymphoma (ATLL). Mogamulizumab (anti-CCR4 monoclonal antibody; Mog) was recently approved as a treatment for ATLL in Japan. Major concerns exist about t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of clinical oncology 2016-10, Vol.34 (28), p.3426-3433
Hauptverfasser:	Fuji, Shigeo, Inoue, Yoshitaka, Utsunomiya, Atae, Moriuchi, Yukiyoshi, Uchimaru, Kaoru, Choi, Ilseung, Otsuka, Eiichi, Henzan, Hideho, Kato, Koji, Tomoyose, Takeaki, Yamamoto, Hisashi, Kurosawa, Saiko, Matsuoka, Ken-Ichi, Yamaguchi, Takuhiro, Fukuda, Takahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adrenal Cortex Hormones - therapeutic use Adult Aged Antibodies, Monoclonal, Humanized - adverse effects Antibodies, Monoclonal, Humanized - therapeutic use Antineoplastic Combined Chemotherapy Protocols - adverse effects Antineoplastic Combined Chemotherapy Protocols - therapeutic use Databases, Factual Female Graft vs Host Disease - chemically induced Graft vs Host Disease - drug therapy Graft vs Host Disease - etiology Graft vs Host Disease - immunology Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic Stem Cell Transplantation - methods Humans Leukemia-Lymphoma, Adult T-Cell - drug therapy Leukemia-Lymphoma, Adult T-Cell - mortality Leukemia-Lymphoma, Adult T-Cell - therapy Male Middle Aged Retrospective Studies Survival Rate Transplantation, Homologous Young Adult
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!