NF-κB dysregulation in multiple myeloma

Abstract The nuclear factor-κB (NF-κB) transcription factor family plays critical roles in the pathophysiology of hematologic neoplasias, including multiple myeloma. The current review examines the roles that this transcription factor system plays in multiple myeloma cells and the nonmalignant acces...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Seminars in cancer biology 2016-08, Vol.39, p.68-76
Hauptverfasser:	Matthews, Geoffrey M., Ph.D, de Matos Simoes, Ricardo, Ph.D, Dhimolea, Eugen, Ph.D, Sheffer, Michal, Ph.D, Gandolfi, Sara, M.D, Dashevsky, Olga, Ph.D, Sorrell, Jeffrey D., B.A, Mitsiades, Constantine S., M.D., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Hematology, Oncology and Palliative Medicine Humans Microenvironment Molecular Targeted Therapy - methods Multiple Myeloma - drug therapy Multiple Myeloma - genetics Multiple Myeloma - metabolism Myeloma NF-kappa B - genetics NF-kappa B - metabolism NF-kappaB Proteasome inhibitors Signal Transduction Stromal cells Tumor Microenvironment
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!