FISHing in the dark: How the combination of FISH and conventional karyotyping improves the diagnostic yield in CpG‐stimulated chronic lymphocytic leukemia

Despite significant advances in molecular genetic approaches, fluorescence in situ hybridization (FISH) remains the gold standard for the diagnostic evaluation of genomic aberrations in patients with chronic lymphocytic leukemia (CLL). Efforts to improve the diagnostic utility of molecular cytogenet...

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Veröffentlicht in:	American journal of hematology 2016-10, Vol.91 (10), p.978-983
Hauptverfasser:	Dubuc, Adrian M., Davids, Matthew S., Pulluqi, Mirela, Pulluqi, Olja, Hoang, Kevin, Hernandez‐Sánchez, Jesus M., Schlich, Cathy, Hernández‐Rivas, Jesus M., Brown, Jennifer R., Dal Cin, Paola
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Chromosome Aberrations Clone Cells - pathology Cytogenetics Hematology Humans In Situ Hybridization, Fluorescence - methods Karyotyping - methods Leukemia, Lymphocytic, Chronic, B-Cell - diagnosis Leukemia, Lymphocytic, Chronic, B-Cell - etiology Leukemia, Lymphocytic, Chronic, B-Cell - genetics Middle Aged Mitogens - pharmacology Neoplasms, Second Primary - diagnosis Oligodeoxyribonucleotides - pharmacology Single-Cell Analysis Young Adult
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